Structural analysis of chemokine receptor–ligand interactions

M Arimont, SL Sun, R Leurs, M Smit… - Journal of medicinal …, 2017 - ACS Publications
structural chemokine receptor–ligand interactions. This review will present a comparative
analysis of ligand binding pockets in chemokine receptors, … US28 X-ray structures (section 2), …

Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR

MC Bewley, K Springer, YB Zhang, P Freimuth… - Science, 1999 - science.org
… To determine the molecular basis for the specificity and tight affinity of this interaction (3),
we crystallized and determined the structure of the Ad12 knob alone and in complex with …

[HTML][HTML] Structural analysis of receptor tyrosine kinases

SR Hubbard - Progress in biophysics and molecular biology, 1999 - Elsevier
Structure of the first three domains of the IGF1 receptor. Shown is a ribbon diagram of the
L1… An important feature revealed by the structure is the interaction between the L1 domain and …

Structure and receptor binding

T Jackson, AMQ King, DI Stuart, E Fry - Virus research, 2003 - Elsevier
… , structural studies have illuminated receptor interactions … of FMDV lend it to detailed structural
analysis, and this has … its cellular receptors and uncoats during the process of cell entry; …

[HTML][HTML] Structure analysis of the receptor binding of 2019-nCoV

Y Chen, Y Guo, Y Pan, ZJ Zhao - Biochemical and biophysical research …, 2020 - Elsevier
… a structural analysis of the receptor binding domain (RBD) of spike glycoprotein responsible
for entry of coronaviruses into host cells. The … ACE2 and RDB interaction was analyzed by …

Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing …

I Mercurio, V Tragni, F Busto, A De Grassi… - Cellular and Molecular …, 2021 - Springer
… proteins under investigation for performing a comparative structural analysis, due to its
ability in providing a sequence-independent structure-based pairwise alignment. Notably, the “…

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR

M Downes, MA Verdecia, AJ Roecker, R Hughes… - Molecular cell, 2003 - cell.com
… Here we describe the discovery and structure/… interaction between the receptor and its
coactivator. The fluorescent tagging of both the receptor and a peptide containing the receptor

Pharmacogenomic and structural analysis of constitutive G protein–coupled receptor activity

MJ Smit, HF Vischer, RA Bakker… - Annu. Rev …, 2007 - annualreviews.org
receptor activity and the pharmacogenomic and structural aspects of constitutive receptor
This interaction seems to exert a key role in receptor stabilization, contributing to constitutive …

Structural biology of the T-cell receptor: insights into receptor assembly, ligand recognition, and initiation of signaling

KW Wucherpfennig, E Gagnon… - Cold Spring …, 2010 - cshperspectives.cshlp.org
… This Vβ8 interaction motif has been seen in structures with different IA alleles, Vα segments,
and peptides, and mutation of these TCRβ residues reduced or abolished activation by a …

Structure-function analysis of the β-adrenergic receptor

RAF Dixon, IS Sigal, CD Strader - Cold Spring Harbor …, 1988 - symposium.cshlp.org
… On the basis of this similarity in protein structure and the common G-protein-based signal
transduction mechanism shared by these receptors, we proposed that the interactions between …