… of the mechanisms of integrin bidirectional signaling across the … In this review, we focus on
integrin structure as it relates to … structural basis for talin and filamin binding to the integrin β …

… on these exciting recent advances on theconformational regulation of ligand binding by
integrin I domains and placesthem within the broader context of integrin structure and function. …

… of specific integrin heterodimers. Structural data obtained from X-ray crystallography and
nuclear magnetic resonance (NMR) have provided insight into the structural basis for integrin …

… Integrins are a structurally elaborate family of adhesion molecules that transmit signals …
large-scale structural rearrangements. By regulating cell-cell and cell-matrix contacts, integrins …

… to which we understand the structural basis for these interaction varies among different
integrin–ligand pairs, because of the limited number of high-resolution crystal structures thus far …

… and structural studies of integrin regulation. Due to the large number of articles dealing with
integrins, … and rewarding directions of contemporary research on cell adhesion and integrins. …

… This review covers the topics of integrin shape and dimerization, models for integrin structure,
mapping of ligand binding sites, and … The function of specific integrins in vivo, and all …

… turn, structural changes that convey distinct signals to the cell interior. The structural basis of
this … In this perspective, we develop a new hypothesis for integrin activation based on recent …

… We have determined the crystal structure of a complex between the I domain of integrin …
both a basis for affinity regulation and a pathway for signal transduction. The structural features …

… a structural basis of integrin–ligand interaction. It presents schematically the domains within
the integrin α … understand how integrins bind their ligands, a three-dimensional structure is …