… structureactivity relationships, in order to show structural requirements implicated in the
anticancer activity of … , which might help to rationalize their development as antitumor agents. …

… antitumor activity but had lower DNA binding than 2 (log K for bindingto poly[d(AT)] was 5.41
and 5.97, respectively), we undertook a structure-activity … -intercalating antitumor agents and …

… 1) as potential anticancer agents covering articles published between 2010 and 2020,
and the mechanisms of action as well as the structure-activity relationships (SARs) are also …

… and in vivo potency, revealing their potential as putative anticancer drugs. In this review,
we … potential anticancer agents, and the mechanisms of action, as well as the structure-activity …

Due to the profound cytotoxicities and interesting biochemical aspects, phenanthroindolizidine
alkaloids have received an attention as potential therapeutic leads. To define the features …

… as potential antitumor agents, we have explored the structure–activity relationships (SAR) of
… Their potent antitumor activities correlated with their potent NF-κB-inhibitory effects and their …

… under intense scrutiny as a potential antitumor agent, since it shows remarkable activity
against advanced experimental colontumors in mice,1 5"3 high activity as a biological response …

… to assess the potentials of these new compounds as cancer chemotherapeutic agents. The
… can be used as guidelines for further improvement of RR inhibitors as anticancer agents. …

… of a new class of antitumor agent, the dibasic 9-aminoacridine-4-carboxamides.1 2These
compounds fall into the general group of DNA-binding agents, binding tightly to double-…

Narciclasine (1) is a plant growth regulator that has been previously demonstrated to be
proapoptotic to cancer cells at high concentrations (≥1 μM). Data generated in the present …