Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation

S Kääb, D Darbar, C van Noord, J Dupuis… - European heart …, 2009 - academic.oup.com
… Several genetic loci for Mendelian forms of … atrial flutter, as described previously: 28 (i) at
baseline and during follow-up examinations, 10 s 12-lead ECGs were recorded at the research

Heritability of atrial fibrillation

LC Weng, SH Choi, D Klarin, JG Smith… - Circulation …, 2017 - Am Heart Assoc
… Our study should be interpreted in the context of the study design. First, our … substantially
to atrial fibrillation risk. Nevertheless, established disease loci for atrial fibrillation, arrhythmias, …

Twelve–single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke

H Tada, D Shiffman, JG Smith, M Sjögren, SA Lubitz… - Stroke, 2014 - Am Heart Assoc
… in the GRS of the current study and the 12th SNP in both AF-GRS studies was in the same
… -GRS comprising 12 SNPs in the same 9 genetic loci we report here. They found that this AF…

Common variation in atrial fibrillation: navigating the path from genetic association to mechanism

NR Tucker, S Clauss, PT Ellinor - Cardiovascular research, 2016 - academic.oup.com
… of studies that identified many additional AF risk loci. In 2012, a meta-analysis in individuals
of European and Japanese descent uncovered an additional six loci … four independent loci at …

Genetic susceptibility to atrial fibrillation is associated with atrial electrical remodeling and adverse post-ablation outcome

GR Wong, CJ Nalliah, G Lee, A Voskoboinik… - Clinical …, 2020 - jacc.org
… 4q25 locus remains the most significant genomewide association study locus identified to …
chromosome 4q25 independently associated with AF risk. The strongest association has been …

Risk factors and genetics of atrial fibrillation

JMB Anumonwo, J Kalifa - Heart failure clinics, 2016 - heartfailure.theclinics.com
… Lifetime risk for development of atrial fibrillation the framingham heart study. … This article
presents a simplified review of the AF risk factors, including emerging genetic risks. Each …

Genetic and clinical risk prediction model for postoperative atrial fibrillation

MJ Kolek, JD Muehlschlegel, WS Bush… - … : Arrhythmia and …, 2015 - Am Heart Assoc
… Clinical variables previously associated with PoAF and 13 SNPs at loci associated with
atrial fibrillation in genome-wide association studies were considered. PoAF occurred in 30% …

Rare and Common Genetic Variation Underlying Atrial Fibrillation Risk

OB Vad, LM Monfort, C Paludan-Müller… - JAMA …, 2024 - jamanetwork.com
… analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
 … in a locus near PKP2 have previously been associated with AF in GWASs, and our study

[HTML][HTML] Gene-gene interaction analyses for atrial fibrillation

H Lin, M Mueller-Nurasyid, AV Smith, DE Arking… - Scientific reports, 2016 - nature.com
… Given that our current study only tested interactions with known AF loci, we are also
planning to expand our analyses to all interactions with the increasing sample size and more …

Mapping a novel locus for familial atrial fibrillation on chromosome 10p11-q21

PGA Volders, Q Zhu, C Timmermans, PMH Eurlings… - Heart Rhythm, 2007 - Elsevier
locus for AF on chromosome 10p11-q21, which provides further evidence of genetic
heterogeneity in this arrhythmia… In the present study, we mapped a novel genetic locus for AF on …