[HTML][HTML] Gefitinib or erlotinib in the treatment of advanced non-small cell lung cancer

YY Shao, CC Lin, CH Yang - Discovery Medicine, 2010 - discoverymedicine.com
… factor receptor, gefitinib and erlotinib, have changed the treatment paradigm of advanced
non-… Many phase II or III studies have proven the efficacy of gefitinib or erlotinib as the first-line, …

[HTML][HTML] Response to gefitinib and erlotinib in Non-small cell lung cancer: a retrospective study

IF Emery, C Battelli, PL Auclair, K Carrier, DM Hayes - BMC cancer, 2009 - Springer
… in the gefitinib and 17% in the erlotinib group discontinued therapy due to … treatment were,
respectively, 2.8 and 7.6 months in the erlotinib group, and 2.4 and 5.0 months in the gefitinib

[HTML][HTML] Phase II study of erlotinib as a salvage treatment for non-small-cell lung cancer patients after failure of gefitinib treatment

DH Lee, SW Kim, C Suh, DH Yoon, EJ Yi, JS Lee - Annals of oncology, 2008 - Elsevier
… We conducted a phase II study of erlotinib after failure of gefitinib treatment in patients with …
our study, of the 15 patients who benefited from gefitinib, two benefited from erlotinib treatment

Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations

JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
… The present study analyzed experiences in treating a large population of NSCLC patients
with gefitinib and erlotinib in order to reveal the trend on drug selection between the two TK …

[HTML][HTML] A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations

JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - British journal of …, 2017 - nature.com
Treatment schedule … at a 1 : 1 ratio to receive oral erlotinib 150 mg or gefitinib 250 mg once
daily. Second- and further-line treatments were defined as second line in the present study. …

[HTML][HTML] Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: a systematic review

R Feld, SS Sridhar, FA Shepherd, JA Mackay… - Journal of Thoracic …, 2006 - Elsevier
… A number of Lung Disease Site Group members, including two of the lead authors of this
systematic review, have been research investigators on clinical trials of gefitinib or erlotinib, …

[HTML][HTML] Comparison of the effectiveness of erlotinib, gefitinib, and afatinib for treatment of non‑small cell lung cancer in patients with common and rare EGFR gene …

P Krawczyk, DM Kowalski, R Ramlau… - Oncology …, 2017 - spandidos-publications.com
… This study was the first to directly compare EGFR-TKIs treatment efficacy in … erlotinib- and
gefitinib-treated groups (11.7 vs. 14.5 months; P=0.507) in a retrospective case-control study of …

[HTML][HTML] Risk of treatment-related toxicities from EGFR tyrosine kinase inhibitors: a meta-analysis of clinical trials of gefitinib, erlotinib, and afatinib in advanced EGFR …

PN Ding, SJ Lord, V Gebski, M Links, V Bray… - Journal of Thoracic …, 2017 - Elsevier
… entry, because we recognized that a significant proportion of patients included in this
study did not have EGFR activating mutation and may have had a shorter duration of …

[HTML][HTML] A comparative study on erlotinib & gefitinib therapy in non-small cell lung carcinoma patients

P Thomas, B Vincent, C George… - … of Medical Research, 2019 - journals.lww.com
study showed that erlotinib and gefitinib had similar effectiveness but gefitinib had a better
safety profile compared to erlotiniberlotinib and gefitinib for treating NSCLC in our study

Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials

M Burotto, EE Manasanch, J Wilkerson, T Fojo - The oncologist, 2015 - academic.oup.com
… The objective of this study was to compare the efficacy and toxicity of erlotinib, … We selected
all randomized studies of erlotinib or gefitinib as treatment of advanced or metastatic stage …