[HTML][HTML] Erlotinib has better efficacy than gefitinib in adenocarcinoma patients without EGFR-activating mutations, but similar efficacy in patients with EGFR-activating …

WS Wu, YM Chen, CM Tsai… - Experimental and …, 2012 - spandidos-publications.com
study was to compare the efficacy of gefitinib and erlotinib in … compares gefitinib and
erlotinib treatment, not to mention a study … In the present study, we retrospectively evaluated the …

Phase II study of erlotinib for acquired resistance to gefitinib in patients with advanced non-small cell lung cancer

A Horiike, N Yamamoto, H Tanaka… - … Research, 2014 - ar.iiarjournals.org
study were as follows: histologically confirmed NSCLC, age 20 years or over, relapsed after
gefitinib treatment … prior gefitinib therapy to specify treatment effects of erlotinib after failure of …

[HTML][HTML] Clinical efficacy of erlotinib, a salvage treatment for non-small cell lung cancer patients following gefitinib failure

KM Cho, B Keam, TM Kim, SH Lee… - The Korean Journal of …, 2015 - ncbi.nlm.nih.gov
study was to identify predictive factors for erlotinib treatment … In the present study, we found
that the PFS of prior gefitinib is … for the clinical efficacy of erlotinib following gefitinib failure. A …

Erlotinib for frontline treatment of advanced non–small cell lung cancer: a phase II study

G Giaccone, M Gallegos Ruiz, T Le Chevalier… - … Cancer Research, 2006 - AACR
… randomized studies that investigated erlotinib or gefitinib in … phase II study of single-agent
erlotinib as first-line therapy in … studies on tumor samples of patients entered in the study to …

[HTML][HTML] Erlotinib versus gefitinib for control of leptomeningeal carcinomatosis in non–small-cell lung cancer

E Lee, B Keam, DW Kim, TM Kim, SH Lee… - Journal of Thoracic …, 2013 - Elsevier
… , erlotinib or gefitinib. The purpose of this study was to assess efficacies of erlotinib and gefitinib
… The comparison of erlotinib and gefitinib in treatment of LMC from NSCLC has not been …

Erlotinib in cancer treatment

MA Bareschino, C Schettino, T Troiani, E Martinelli… - Annals of oncology, 2007 - Elsevier
… This study showed that erlotinib significantly prolonged … of erlotinib single-agent therapy
in recurrent GBM [38]. In colorectal cancer, single-agent treatment with TKIs (erlotinib, gefitinib) …

Use of the epidermal growth factor receptor inhibitors gefitinib, erlotinib, afatinib, dacomitinib, and icotinib in the treatment of non-small-cell lung cancer: a systematic …

PM Ellis, N Coakley, R Feld, S Kuruvilla, YC Ung - Current oncology, 2015 - mdpi.com
… No relevant systematic reviews that answered our research questions were identified. …
The os with gefitinib therapy trended longer in the mutation-positive subgroup (hr: 0.78; 95% ci: …

The Impact of Initial Gefitinib or Erlotinib versus Chemotherapy on Central Nervous System Progression in Advanced Non–Small Cell Lung Cancer with EGFR …

S Heon, BY Yeap, NI Lindeman, VA Joshi… - … Cancer Research, 2012 - AACR
Study design and patients Patients were eligible for this study if they had stage IV NSCLC or
… mutations and were treated with gefitinib, erlotinib, or chemotherapy as their initial systemic …

Risk of interstitial lung disease with gefitinib and erlotinib in advanced non-small cell lung cancer: a systematic review and meta-analysis of clinical trials

L Shi, J Tang, L Tong, Z Liu - Lung Cancer, 2014 - Elsevier
… in patients treated with gefitinib or erlotinib varied substantially among trials. In a phase II study
… Our search yielded a total of 496 potentially relevant studies with gefitinib or erlotinib. The …

[HTML][HTML] First-line erlotinib versus gemcitabine/cisplatin in patients with advanced EGFR mutation-positive non-small-cell lung cancer: analyses from the phase III …

YL Wu, C Zhou, CK Liam, G Wu, X Liu, Z Zhong, S Lu… - Annals of oncology, 2015 - Elsevier
… Afatinib and gefitinib have also demonstrated efficacy in the first-line … our study was that
specific combinations of post-study therapy were not documented, eg maintenance erlotinib plus …