Upfront gefitinib/erlotinib treatment followed by concomitant radiotherapy for advanced lung cancer: a mono-institutional experience

CC Chang, KH Chi, SJ Kao, PS Hsu, YW Tsang… - Lung cancer, 2011 - Elsevier
… This study included 25 patients with stage IIIb or IV non-squamous cell, non-small cell lung
… to upfront TKI treatment (gefitinib 250 mg/d or erlotinib150 mg/d) were treated with multi-…

Duration of prior gefitinib treatment predicts survival potential in patients with lung adenocarcinoma receiving subsequent erlotinib

K Asami, M Kawahara, S Atagi, T Kawaguchi, K Okishio - Lung Cancer, 2011 - Elsevier
… Forty-two patients with lung adenocarcinoma were reviewed in the present study. All … All
patients in the present study were affected by rash of some grade while receiving erlotinib. The …

Gefitinib or Erlotinib vs Chemotherapy for EGFR Mutation-Positive Lung Cancer: Individual Patient Data Meta-Analysis of Overall Survival

CK Lee, L Davies, YL Wu, T Mitsudomi… - JNCI: Journal of the …, 2017 - academic.oup.com
study, the primary objective was to determine the pooled overall treatment effect on OS of
firstline therapy with gefitinib … this meta-analysis of gefitinib and erlotinib as most of the included …

Comparing the effects of afatinib with gefitinib or Erlotinib in patients with advanced-stage lung adenocarcinoma harboring non-classical epidermal growth factor …

YC Shen, GC Tseng, CY Tu, WC Chen, WC Liao… - Lung Cancer, 2017 - Elsevier
… No study has compared these two generations of EGFR-TKIs … retrospective study to assess
the efficacy of gefitinib/erlotinib … between the gefitinib/erlotinib and afatinib treatment groups, …

Gefitinib provides similar effectiveness and improved safety than erlotinib for advanced non-small cell lung cancer: A meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - Medicine, 2018 - journals.lww.com
Gefitinib and erlotinib have been widely used to treat advanced NSCLC during the past
decade. By analyzing 40 high quality studies, we compared the antitumor effectiveness and …

A review of erlotinib and its clinical use

PA Tang, MS Tsao, MJ Moore - Expert opinion on pharmacotherapy, 2006 - Taylor & Francis
Erlotinib has an established role in the treatment of advanced, … Erlotinib and gefitinib are
reversible tyrosine kinase … In the Phase I study of erlotinib in combination with carboplatin and …

[HTML][HTML] Comparison of effectiveness of Gefitinib, Erlotinib, and Afatinib in advanced non-small cell lung cancer patients with EGFR mutation positive in Indonesian …

N Sutandyo, A Hanafi, M Jayusman - Chinese journal of lung …, 2019 - ncbi.nlm.nih.gov
… This study aims to compare the effectiveness of first line TKIs; gefitinib, erlotinib, and
afatinib in the treatment of advanced stage NSCLC patients with EGFR mutation positive in the …

[HTML][HTML] The different central nervous system efficacy among gefitinib, erlotinib and afatinib in patients with epidermal growth factor receptor mutation-positive non …

HA Jung, SY Woo, SH Lee, JS Ahn… - … Cancer Research, 2020 - ncbi.nlm.nih.gov
… discretion in this study, the TKI treatment chosen for patients with brain metastasis may
have been affected by physician awareness of previous studies favoring erlotinib or afatinib in …

Shikonin sensitizes wild‑type EGFR NSCLC cells to erlotinib and gefitinib therapy

YL Li, X Hu, QY Li, F Wang… - Molecular …, 2018 - spandidos-publications.com
… of the present study suggested that shikonin could promote erlotinib/gefitinib-induced apoptosis
… The dose of erlotinib/gefitinib selected in the present study was not expected to exhibit …

[HTML][HTML] Comparison of first-generation EGFR-TKIs (gefitinib, erlotinib, and icotinib) as adjuvant therapy in resected NSCLC patients with sensitive EGFR mutations

Q He, J Liu, X Cai, M He, C Li, H Liang… - … Cancer Research, 2021 - ncbi.nlm.nih.gov
… of this study were to compare the efficacy among three first-generation EGFR-TKIs as adjuvant
treatment … Finally, treatment selection bias was inevitable in this study; however, since all …