Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations

JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
study analyzed experiences in treating a large population of NSCLC patients with gefitinib
and erlotinib in … We stratified all patients according to different lines of gefitinib or erlotinib. The …

Phase II study of erlotinib in advanced non–small-cell lung cancer after failure of gefitinib

BC Cho, CK Im, MS Park, SK Kim, J Chang… - Journal of clinical …, 2007 - ascopubs.org
… of six patients who benefited from erlotinib in our studyerlotinib may be more efficacious
than gefitinib on wild-type EGFR by higher-affinity binding to the EGFR kinase domain. Erlotinib

Response to gefitinib and erlotinib in Non-small cell lung cancer: a retrospective study

IF Emery, C Battelli, PL Auclair, K Carrier, DM Hayes - BMC cancer, 2009 - Springer
… our lung cancer patients to compare the benefits derived from erlotinib and gefitinib and to
… We subsequently analyzed tumor tissue from a subgroup of these patients for a pilot study to …

A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations

JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - British journal of …, 2017 - nature.com
… The present study identified no significant differences in efficacy or toxicity profile between
first-line erlotinib and gefitinib for patients with EGFR-mutant disease, and these results could …

[HTML][HTML] Different efficacies of erlotinib and gefitinib in taiwanese patients with advanced non-small cell lung cancer: a retrospective multicenter study

WC Fan, CJ Yu, CM Tsai, MS Huang, CL Lai… - Journal of Thoracic …, 2011 - Elsevier
… non-small cell lung cancer (NSCLC) patients in East Asia. The objective of this study was
to compare the efficacy of gefitinib and erlotinib in Taiwanese patients with advanced NSCLC. …

Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy

ST Kim, JE Uhm, J Lee, J Sun, I Sohn, SW Kim… - Lung Cancer, 2012 - Elsevier
… , this study demonstrated that both gefitinib and erlotinibstudy with inclusion of both
gefitinib and erlotinib in a properly conducted and powered phase III trial in an enriched patient

Comparison of adverse events and efficacy between gefitinib and erlotinib in patients with non-small-cell lung cancer: a retrospective analysis

T Yoshida, K Yamada, K Azuma, A Kawahara, H Abe… - Medical oncology, 2013 - Springer
… All patients in this study were included in the analysis of AEs. Comparisons … study will be
needed to validate our results. Currently, a phase III trial of gefitinib versus erlotinib for patients

[HTML][HTML] Gefitinib or erlotinib in the treatment of advanced non-small cell lung cancer

YY Shao, CC Lin, CH Yang - Discovery Medicine, 2010 - discoverymedicine.com
… II or III studies have proven the efficacy of gefitinib or erlotinib as … However, it is not clear
whether gefitinib or erlotinib has … of smokers and female patients, but the ISEL study (gefitinib vs. …

Comparison of the effectiveness of erlotinib, gefitinib, and afatinib for treatment of non-small cell lung cancer in patients with common and rare EGFR gene mutations

P Krawczyk, DM Kowalski, R Ramlau… - Oncology …, 2017 - spandidos-publications.com
… The aim of the study was to compare the efficacies of EGFR‑TKIs in patients with common
(exon 19 deletions and exon 21 p.Leu858Arg) and rare EGFR mutations. A retrospective …

Randomized phase III study comparing gefitinib with erlotinib in patients with previously treated advanced lung adenocarcinoma: WJOG 5108L

Y Urata, N Katakami, S Morita, R Kaji… - Journal of Clinical …, 2016 - ascopubs.org
… with lung adenocarcinoma were randomly assigned to receive gefitinib or erlotinib. This
study aimed to investigate the noninferiority of gefitinib compared with erlotinib. The primary end …