[HTML][HTML] A retrospective comparison of the clinical efficacy of gefitinib, erlotinib, and afatinib in Japanese patients with non-small cell lung cancer

A Fujiwara, M Yoshida, H Fujimoto, H Nakahara… - … research, 2018 - ncbi.nlm.nih.gov
… However, whether gefitinib, erlotinib, or afatinib is most … study was to compare the effectiveness
of gefitinib, erlotinib, and afatinib. We retrospectively reviewed the records of 310 patients

Gefitinib or erlotinib as maintenance therapy in patients with advanced stage non-small cell lung cancer: a systematic review

X Chen, Y Liu, OD Røe, Y Qian, R Guo, L Zhu, Y Yin… - PloS one, 2013 - journals.plos.org
… based on individual patient data, and not all studies provided detailed subgroups analysis.
… This study investigated maintenance gemcitabine or erlotinib versus observation, following …

Clinical outcomes of gefitinib and erlotinib in patients with NSCLC harboring uncommon EGFR mutations: A pooled analysis of 438 patients

C Wang, K Zhao, S Hu, W Dong, Y Gong, M Li, C Xie - Lung Cancer, 2022 - Elsevier
… The purpose of this study was to investigate the outcomes of gefitinib and erlotinib in patients
… In this study, patients treated with gefitinib had a significantly better ORR and longer PFS …

Erlotinib efficacy and cerebrospinal fluid concentration in patients with lung adenocarcinoma developing leptomeningeal metastases during gefitinib therapy

T Masuda, N Hattori, A Hamada, H Iwamoto… - Cancer chemotherapy …, 2011 - Springer
… This value is much lower than the penetration of erlotinib measured in this study (ranging
from 2.5 to 13.3%). Although the oral bioavailabilities are reported as almost equal between …

Comparison of effectiveness and adverse effects of gefitinib, erlotinib and icotinib among patients with non‑small cell lung cancer: A network meta‑analysis

Y Liu, Y Zhang, G Feng, Q Niu… - Experimental and …, 2017 - spandidos-publications.com
… , gefitinib, erlotinib and icotinib had similar effectiveness for the treatment of patients with …
In the current study, a network meta-analysis was performed to compare the effectiveness …

[HTML][HTML] Erlotinib versus gefitinib for control of leptomeningeal carcinomatosis in non–small-cell lung cancer

E Lee, B Keam, DW Kim, TM Kim, SH Lee… - Journal of Thoracic …, 2013 - Elsevier
… was more effective in obtaining cytologic negative conversion of the CSF than gefitinib for a
subgroup of patients. The results of this study suggest that erlotinib provides better control of …

Phase II study of erlotinib in patients with malignant pleural mesothelioma: a Southwest Oncology Group Study

LL Garland, C Rankin, DR Gandara… - Journal of Clinical …, 2007 - ascopubs.org
… in this study of erlotinib. One-year survival rate for patients treated with gefitinib was 32% (95…
than the rate reported here for erlotinib, although CIs for both studies were large. Similar to …

Comparison of gefitinib, erlotinib and afatinib in non‐small cell lung cancer: a meta‐analysis

Z Yang, A Hackshaw, Q Feng, X Fu… - … journal of cancer, 2017 - Wiley Online Library
… Eight randomized trials and 82 cohort studies with a total of 17,621 patients were included
for analysis. Gefitinib and erlotinib demonstrated comparable effects on progression-free …

[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib

Y Kim, SH Lee, JS Ahn, MJ Ahn… - Cancer Research and …, 2019 - synapse.koreamed.org
patients treated with first-line afatinib, gefitinib, or erlotinib for … Our purpose of this study is
to investigate how afatinib is used in … clinical outcomes compared with gefitinib or erlotinib. …

The Current Situation: Erlotinib (Tarceva®) and Gefitinib (Iressa®) in Non-Small Cell Lung Cancer

RL Comis - The oncologist, 2005 - academic.oup.com
… , phase III study of single-agent erlotinib at a dose of 150 mg daily in patients with locally …
Interestingly, the HRs for erlotinib in the two patient subsets in which gefitinib appears to …