… different efficacy of gefitinib or erlotinib according to epidermal growth factor receptor exon 19 and exon 21 mutations in Korean non-small cell lung cancer patients

JM Sun, YW Won, ST Kim, JH Kim, YL Choi… - … of cancer research and …, 2011 - Springer
… or L858R mutations, 77 patients were treated with gefitinib or erlotinib according to their
physician’s discretion and were included in this study. The remaining 67 patients were either not …

Effectiveness of erlotinib in advanced non-small cell lung cancer in cases of gefitinib resistance after treatment of more than 6 months

H Saito, S Murakami, T Kondo, F Oshita… - Oncology Research …, 2012 - karger.com
Patients and Methods: We retrospectively studied gefitinib-resistant NSCLC … We retrospectively
studied gefitinib-resistant NSCLC p atients treated with erlotinib after long periods of SD. …

Study of efficacy and safety of pulsatile administration of high‐dose gefitinib or erlotinib for advanced non‐small cell lung cancer patients with secondary drug …

Y Zhu, Y Du, H Liu, T Ma, Y Shen, Y Pan - Thoracic cancer, 2016 - Wiley Online Library
… The objective of the study was to observe the efficacy and safety of pulsatile administration
of high-dose gefitinib or erlotinib in patients with advanced non-small cell lung cancer (…

[HTML][HTML] Symptom and quality of life benefit of afatinib in advanced non–small-cell lung cancer patients previously treated with erlotinib or gefitinib: results of a …

V Hirsh, J Cadranel, XJ Cong, D Fairclough… - Journal of Thoracic …, 2013 - Elsevier
patients with lung adenocarcinoma (stage IIIb/IV), who had progressed after chemotherapy
(1–2 lines) and at least 12 weeks of erlotinib or gefitinib… reported from this study, in addition to …

[HTML][HTML] The different central nervous system efficacy among gefitinib, erlotinib and afatinib in patients with epidermal growth factor receptor mutation-positive non …

HA Jung, SY Woo, SH Lee, JS Ahn… - … Cancer Research, 2020 - ncbi.nlm.nih.gov
Study subjects and data collection This study included 599 patients with EGFR-mutant
NSCLC who started first-line gefitinib, erlotinib, afatinib treatment for advanced NSCLC at …

… after Tyrosine Kinase Inhibitor Discontinuation in Patients with EGFR-Mutant Lung Cancer and Acquired Resistance to Erlotinib or Gefitinib: Implications for Clinical …

JE Chaft, GR Oxnard, CS Sima, MG Kris, VA Miller… - … cancer research, 2011 - AACR
patients enrolled on clinical trials of agents to treat acquired resistance to erlotinib or gefitinib
However, in this study there was not a lower rate of disease flare in patients with T790M-…

Are erlotinib and gefitinib interchangeable, opposite or complementary for non-small cell lung cancer treatment? Biological, pharmacological and clinical aspects

G Bronte, C Rolfo, E Giovannetti, G Cicero… - Critical reviews in …, 2014 - Elsevier
… This study analyzed 95 patients enrolled in EURTAC trial for T790M end P53 mutations,
EML4-ALK translocation and BIM mRNA expression levels. The results showed that OS for …

Current Knowledge and Future Directions of the Selective Epidermal Growth Factor Receptor Inhibitors Erlotinib (Tarceva®) and Gefitinib (Iressa®)

WS Siegel-Lakhai, JH Beijnen, JHM Schellens - The oncologist, 2005 - academic.oup.com
… I studies of gefitinib and erlotinib were performed in patients … , phase II studies with gefitinib
or erlotinib in patients with … Gefitinib was studied in two multicenter trials: the Iressa ® Dose …

[HTML][HTML] Gefitinib provides similar effectiveness and improved safety than erlotinib for east Asian populations with advanced non–small cell lung cancer: a meta …

W Zhang, Y Wei, D Yu, J Xu, J Peng - BMC cancer, 2018 - Springer
… ) is comparable between gefitinib and erlotinib for treating East Asian patients with NSCLC.
… that an increasing number of studies have used gefitinib and erlotinib as first-line treatment …

[HTML][HTML] Gefitinib provides similar effectiveness and improved safety than erlotinib for advanced non-small cell lung cancer: A meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - Medicine, 2018 - journals.lww.com
… After screening, 40 studies involving 9376 patients (5602 patients in the gefitinib group
and 3774 patients in the erlotinib group) were included for the final analysis (Fig. 1). [6,8–13,17–…