Teplizumab for treatment of type 1 diabetes (Protege study): 1-year results from a randomised, placebo-controlled trial

N Sherry, W Hagopian, J Ludvigsson, SM Jain… - The Lancet, 2011 - thelancet.com
… Our study of immune therapy in recent-onset type 1 diabetes did not show any significant
between-group differences in the primary and secondary outcomes (panel). The primary …

[HTML][HTML] Effects of insulin in relatives of patients with type 1 diabetes mellitus

… Prevention Trial–Type 1 Diabetes Study … - … England Journal of …, 2002 - Mass Medical Soc
diabetes, insulin at the dosage used in this study does not delay or prevent type 1 diabetes.
(… Type 1 diabetes mellitus occurs in genetically predisposed persons as a consequence of …

Type 1 Diabetes TrialNet–an international collaborative clinical trials network

…, Type 1 Diabetes TrialNet Study Group - Annals of the New …, 2008 - Wiley Online Library
Type 1 Diabetes TrialNet is an international consortium of clinical research centers aimed
at the prevention or delay of type 1 diabetes (T1D). The fundamental goal of TrialNet is to …

The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results

…, Type 1 Diabetes TrialNet Study Group - … diabetes, 2009 - Wiley Online Library
Research Foundation, has formed Type 1 Diabetes – TrialNet to perform further prevention
… of pre-type 1 diabetes in relatives of persons with the disease. We describe in this study the …

Type 1 diabetes

LA DiMeglio, C Evans-Molina, RA Oram - The Lancet, 2018 - thelancet.com
… , a preclinical stage 1 case of type 1 diabetes is defined as the … to overt diabetes, diagnosed
by standard criteria (figure 2B). … Genome-wide association studies have identified over 60 …

[HTML][HTML] Motivational interviewing and self-care in type 1 diabetes: a randomized controlled clinical trial study protocol

D Alvarado-Martel, M Boronat… - Frontiers in …, 2020 - frontiersin.org
… In this study, we aim to evaluate the effect of MI on self-care and HbA1c in people with
type 1 diabetes. Clinical Trial Registration: https://clinicaltrials.gov/ct2/show/NCT03906786, …

… management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes  …

RIG Holt, JH DeVries, A Hess-Fischl, IB Hirsch… - Diabetes …, 2021 - Am Diabetes Assoc
… that the overall prevalence of type 1 diabetes is higher in adults than in children, justifying
our focus on type 1 diabetes in adults (1). The global prevalence of type 1 diabetes is 5.9 per …

Type 1 diabetes mellitus

A Katsarou, S Gudbjörnsdottir, A Rawshani… - Nature reviews Disease …, 2017 - nature.com
… On the basis of this study, T1DM is classified as autoimmune diabetes, regardless of the
presence of obesity or insulin resistance, whereas T2DM requires the presence of insulin …

The 25-year incidence of visual impairment in type 1 diabetes mellitus: the Wisconsin Epidemiologic Study of Diabetic Retinopathy

R Klein, KE Lee, RE Gangnon, BEK Klein - Ophthalmology, 2010 - Elsevier
… Best-corrected visual acuity (VA) was measured using a modification of the Early Treatment
Diabetic Retinopathy Study protocol. Visual impairment and severe VI were defined as best-…

Efficacy of inhaled human insulin in type 1 diabetes mellitus: a randomised proof-of-concept study

JS Skyler, WT Cefalu, IA Kourides, WH Landschulz… - The Lancet, 2001 - thelancet.com
… We did a proof-of-concept study to test the efficacy of this approach in patients with
insulindeficient, C-peptide-negative, type 1 diabetes mellitus. The aim was to determine whether …