… One of the main features of OA is subchondral bone … of subchondral bone exhibit dynamic
changes with OA disease progress, with mainly bone resorption in the early stages and bone …

… subchondral bone in the pathogenesis of cartilage damage has likely been underestimated.
Subchondral bone … , but it may also be important for cartilage metabolism. Contrary to many …

… bony bed occur before the cartilage changes and suggest that this can occur in clinical
conditions. Stiffening of the subchondral bone … of articular cartilage and bone to create maximum …

… of subchondral bone and its importance in cartilage diseases … articular cartilage and
subchondral bone (articular bone plate) … At the same the different stages of cartilage degeneration …

… in subchondral bone architecture. Furthermore, we have found that … of cartilage degeneration
leads to changes in bone parameters which affected deeper levels of subchondral bone. …

… : degeneration of articular cartilage, synovial immunopathogenesis, and changes in subchondral
bone. For … , degeneration of articular cartilage, and subchondral bone remodeling can …

… and spontaneous animal models that have shown a close relationship between the process
of cartilage damage and subchondral bone changes using state-of-the-art quantification of …

… bone mass and thickening of the subchondral bone may in fact be the primary event of joint
degeneration. … bone were associat ed with cartilage degeneration. In a normal, healthy joint …

… of articular cartilage and subchondral bone. Histologic and radiologic changes were …
We hypothesized that the alterations in the cartilage and subchondral bone would depend …

… that the subchondral bone is fragile before the onset of cartilage degeneration and bone
formation is promoted in the subchondral bone before the onset of cartilage degeneration […