… mice and at a peak load of 9.0N in young mice for durations of 1, 2, and 6 weeks. We
hypothesized that the alterations in the cartilage and subchondral bone … by the age of the mice. …

… με at the mid-diaphysis of the tibia. While we did not directly … cortical bone material properties
between FVB and B6 mice were … on bone adaptation in the tibiae of B6 and FVB mice. In B6 …

… study was to quantify subchondral bone changes in a murine … -like changes in the knee joints
of mice using collagenase … of murine tibiae, and analyzed both the subchondral bone plate …

… mice are protected from cartilage damage, and since it is well known that changes in
subchondral bone … sclerosis of the subchondral bone plate was found at the medial tibia in WT …

… walking) and compositional degenerations (a bright and stiff Subchondral Bone (SB)), a
loss of joint space between femur and tibia – massive cartilage degradation –, and several SB …

… We addressed this hypothesis by investigating bone and cartilage changes in the proximal
tibia and patella of knee joints of ovariectomized mice and ovariectomized mice receiving …

… The resulting data was put through an in-house algorithm that defines VOIs for the epiphyseal
trabecular and subchondral cortical bone for both the femur and tibia. Additionally, manual …

… Of note, mice with tibia dislocation were not included in this study. … In summary, subchondral
bone changes in the DMM mouse model occurred rapidly, with bone sclerosis occurred as …

… bone morphological parameters can be reliably measured by in vivo microCT imaging of the
subchondral bone in the mouse tibia. It … subchondral cortical bone and on most subchondral …

… Visualization of subchondral bone changes within the proximal tibia of a single mouse (from
longitudinal group/0–14) at time zero and at 2, 4, and 14 weeks after injection. A, At the …