Elderly patients benefit from second-line cytotoxic chemotherapy: A subset analysis of a randomized phase III trial of pemetrexed compared with docetaxel in patients …

GJ Weiss, C Langer, R Rosell, N Hanna… - Journal of clinical …, 2006 - ascopubs.org
… This analysis shows that elderly patients can have as much benefit from second-line cytotoxic
chemotherapy as younger patients, and this can be achieved with acceptable toxicity rates…

FDA subset analysis of the safety of nivolumab in elderly patients with advanced cancers.

H Singh, G Kim, VE Maher, JA Beaver, LH Pai-Scherf… - 2016 - ascopubs.org
… advanced cancer, an increasing number of elderly patients will be treated with immunotherapy.
… of nivolumab in an elderly patient population. Methods: Eligible patients recieved at least …

Subset analysis of the safety and efficacy of nivolumab in elderly patients with metastatic melanoma

M Freeman, J Weber - Journal for ImmunoTherapy of Cancer, 2015 - search.proquest.com
elderly patients with checkpoint inhibition presents a unique challenge as nearly half of all
malignancies are diagnosed in patients … challenging in older patients given the association of …

[HTML][HTML] Erlotinib for elderly patients with non‑small‑cell lung cancer: Subset analysis from a population‑based observational study by the Ibaraki Thoracic Integrative …

K Kurishima, H Satoh, T Kaburagi… - Molecular and …, 2013 - spandidos-publications.com
patients receiving erlotinib, irrespective of their individual characteristics (14). In this subset
analysis, we evaluated the association of age with the treatment results of erlotinib in patients

… therapy with fluorouracil and oxaliplatin in stage II and elderly patients (between ages 70 and 75 years) with colon cancer: subgroup analyses of the Multicenter …

C Tournigand, T André, F Bonnetain… - Journal of clinical …, 2012 - ascopubs.org
… The results of these subset analyses show no statistically significant benefit (OS and DFS)
for the addition of oxaliplatin to FL as adjuvant treatment for either stage II and elderly patients. …

Myocardial infarction in young patients: an analysis by age subsets.

BD Hoit, EA Gilpin, H Henning, AA Maisel, H Dittrich… - Circulation, 1986 - Am Heart Assoc
… , at 2.6% compared with 10.3% in middle-aged and 24.4% in elderly patients. The
incidence of reinfarction during the1 year of follow-up was similar in all subsets. The statistical …

[HTML][HTML] … Patients Tolerate Palliative Concurrent Chemoradiotherapy for Locally Advanced Non–Small-Cell Lung Cancer Stage III? A Subset Analysis From a Clinical …

HH Strøm, RM Bremnes, SH Sundstrøm… - Clinical Lung Cancer, 2015 - Elsevier
… for elderly patients with lung cancer, we present the data from a subset analysis that
focused on the efficacy, toxicity, and HRQoL in elderly patients included in the phase III trial. …

Safety and efficacy of intravenous acetaminophen in the elderly after major orthopedic surgery: subset data analysis from 3, randomized, placebo-controlled trials

JS Jahr, JB Breitmeyer, C Pan, MA Royal… - American journal of …, 2012 - journals.lww.com
… A recently conducted pharmacokinetic study in elderly patients undergoing orthopedic
surgery suggests that a dose regimen adjustment may be appropriate in the patient group older …

Safety and efficacy of sorafenib in elderly patients (pts)≥ 65 years: A subset analysis from the Advanced Renal Cell Carcinoma Sorafenib (ARCCS) Expanded Access …

RM Bukowski, WM Stadler, RA Figlin… - Journal of Clinical …, 2008 - ascopubs.org
… Because sorafenib is likely to be used in elderly pts with advanced RCC, we evaluated
its safety and efficacy profile in a subset of pts ≥65 years (yrs) who enrolled in the ARCCS …

[HTML][HTML] … subset analysis of randomized phase III study comparing pemetrexed plus carboplatin with docetaxel plus carboplatin as first-line treatment for patients with …

JR Pereira, R Cheng, M Orlando, JH Kim… - Drugs in R&D, 2013 - Springer
… We performed a retrospective analysis of elderly patient subsets (aged ≥65 and ≥70 years)
within a phase III trial evaluating pemetrexed + carboplatin and docetaxel + carboplatin in …