… D 3 receptor structures, we further applied a hybrid, stepwise … In this computational approach,
a pharmacophore model was … Hits identified from pharmacophore searching were further …

… In this study, a ligand-based method, pharmacophore modeling was applied to extract
common and specific chemical features for three opioid receptor subtypes. Then, homology …

… hybrid ligand-based VS protocol that is based on support vector machine (SVM) classification
and pharmacophore … in that the receptor structure was created by homology modeling. The …

… Yeast two-hybrid (Y2H) assay was used to detect the activity … the strategy combining
pharmacophore and molecular docking … differences between the two subtypes of estrogen …

… pharmacophoric … LB 3D pharmacophores and compared the ability of these two approaches
to generate agonist selective pharmacophores and antagonist selective pharmacophores …

… 5-HT 7 receptor antagonists was … receptor-based pharmacophores: first containing features
necessary for high 5-HT 7 R affinity and the other defining selectivity for this receptor subtype. …

… Pharmacophore models of serotonin receptors ligands have been created for above thirty
… with the receptor. During the next twenty years a number of pharmacophore models of 5-HT …

… pharmacophores prompted us to merge them in two hybrid models. The hybrid pharmacophores
… There are two subtypes of estrogen receptors encoded by different genes: ERα and …

… ligand is a hybrid molecule in which two pharmacophores are … heterobivalent ligands may
have pharmacophores that bind to … receptor subtype selectivity and/or enhanced affinity for the …

… modeling for the discovery of novel transient receptor potential … false positive hits, the hybrid
model was more restrictive due to … on metabotropic glutamate receptor subtype 4. J. Med. …