Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS
BR Roberts, JA Tainer, ED Getzoff, DA Malencik… - Journal of molecular …, 2007 - Elsevier
… In humans, familial ALS is an autosomal dominant disease that allows for the formation of …
human mitochondrial MnSOD fails to cause any known degenerative diseases in humans …
human mitochondrial MnSOD fails to cause any known degenerative diseases in humans …
Vascular extracellular superoxide dismutase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation
U Landmesser, R Merten, S Spiekermann, K Büttner… - Circulation, 2000 - Am Heart Assoc
… contributes to endothelial dysfunction in patients with coronary artery disease (CAD). We
therefore determined the activity of extracellular superoxide dismutase (EC-SOD), the major …
therefore determined the activity of extracellular superoxide dismutase (EC-SOD), the major …
Overexpression of human copper, zinc-superoxide dismutase (SOD1) prevents postischemic injury
P Wang, H Chen, H Qin… - Proceedings of the …, 1998 - National Acad Sciences
… With the advent of thrombolytic and other revascularization therapies reperfusion of ischemic
tissues has become a common event in the treatment of important human diseases such as …
tissues has become a common event in the treatment of important human diseases such as …
Oxidative stress, nitric oxide synthase, and superoxide dismutase: a matter of imbalance underlies endothelial dysfunction in the human coronary circulation
EL Schiffrin - Hypertension, 2008 - Am Heart Assoc
… represent common characteristics in vascular disease. … of obstructive coronary artery disease,
coronary artery diameter … ROS generation) and reduced superoxide dismutase activity (an …
coronary artery diameter … ROS generation) and reduced superoxide dismutase activity (an …
Aortic ascorbic acid, trace elements, and superoxide dismutase activity in human aneurysmal and occlusive disease
MA Dubick, GC Hunter, SM Casey… - Proceedings of the …, 1987 - journals.sagepub.com
… in the disease … superoxide dismutase (SOD) activity in tissue samples from 29 patients
with abdominal aortic aneurysms (AAA) and 14 patients wtih atherosclerotic occlusive disease (…
with abdominal aortic aneurysms (AAA) and 14 patients wtih atherosclerotic occlusive disease (…
[HTML][HTML] Activation of superoxide dismutases: putting the metal to the pedal
VC Culotta, M Yang, TV O'Halloran - Biochimica et Biophysica Acta (BBA) …, 2006 - Elsevier
… The strongest connection between SODs and human disease is found for the copper …
disease amyotrophic lateral sclerosis (ALS) [6]. The activity of each of the superoxide dismutase …
disease amyotrophic lateral sclerosis (ALS) [6]. The activity of each of the superoxide dismutase …
Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu, Zn superoxide dismutase
RMF Cardoso, MM Thayer, M DiDonato, TP Lo… - Journal of molecular …, 2002 - Elsevier
… Mutations in human superoxide dismutase (HSOD) have been linked to the familial form of …
Lou Gehrig's disease) is one of the most common neurodegenerative disorders in humans. In …
Lou Gehrig's disease) is one of the most common neurodegenerative disorders in humans. In …
Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression
… diseases, such as cancer, hypertension, diabetes, atherosclerosis, inflammation, and premature
aging. The superoxide dismutases (… ROS and particularly superoxide anion radicals. At …
aging. The superoxide dismutases (… ROS and particularly superoxide anion radicals. At …
Manganese complexes displaying superoxide dismutase activity: a balance between different factors
O Iranzo - Bioorganic chemistry, 2011 - Elsevier
… in humans (Orgotein®). The potential therapeutic application of the SOD enzymes for the
treatment of human diseases … when the SOD derives from non-human sources, short half-lives (…
treatment of human diseases … when the SOD derives from non-human sources, short half-lives (…
Superoxide dismutase and total anti-oxidant levels in various forms of liver diseases
M Irshad, PS Chaudhuri, YK Joshi - Hepatology research, 2002 - Elsevier
… of the body, blood levels of superoxide dismutase (SOD), an … hepatitis in various forms of
liver diseases. A total number of … belonging to these three liver diseases had hepatitis A viral (…
liver diseases. A total number of … belonging to these three liver diseases had hepatitis A viral (…