Superoxide dismutase mimetics

D Salvemini, C Muscoli, DP Riley… - Pulmonary pharmacology …, 2002 - Elsevier
… Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but
exhibit enhanced cell death after axonal injury … Mice lacking extracellular superoxide …

On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies

C Muscoli, S Cuzzocrea, DP Riley… - British journal of …, 2003 - Wiley Online Library
… using various superoxide dismutase mimetics that led to the proposal that superoxide (and/…
, and to the conclusion that superoxide dismutase mimetics can be utilized as therapeutic …

Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine

D Salvemini, S Cuzzocrea - Critical care medicine, 2003 - journals.lww.com
… This review highlights the evidence for a potential therapeutic utility of superoxide dismutase
(SOD) mimetics that remove superoxide in shock and ischemia and reperfusion injury. …

Oxidative stress in neurodegenerative diseases: therapeutic implications for superoxide dismutase mimetics

K Pong - Expert opinion on biological therapy, 2003 - Taylor & Francis
… Antioxidant enzymes, such as superoxide dismutase (SOD), catalase and glutathione perox…
mimetics, small molecules which mimic the activity of endogenous superoxide dismutase, …

A biologically effective fullerene (C60) derivative with superoxide dismutase mimetic properties

SS Ali, JI Hardt, KL Quick, JS Kim-Han… - Free Radical Biology …, 2004 - Elsevier
… C 3 a unique non-metal superoxide dismutase mimetic. C 3 appears to represent the first
of a unique class of non-peptidyl SOD mimetics which may have therapeutic potential. In …

Therapeutic potential of selective superoxide dismutase mimetics

SA Doggrell - Drugs Future, 2002 - access.portico.org
superoxide dismutase (SOD) mimetics are potentially useful in pathological conditions in
which there is an overproduction of the superoxide … selective SOD mimetics that penetrate cell …

Nonpeptidyl mimetics of superoxide dismutase in clinical therapies for diseases.

D Salvemini, DP Riley - Cellular & Molecular Life Sciences, 2000 - search.ebscohost.com
… Under normal circumstances in healthy individuals this radical burden is contained by the
complement of superoxide dismutase (SOD) enzymes present in our cells (mitochondria, Mn-…

Superoxide dismutase mimics as future therapeutics

SL Henke - Expert Opinion on Therapeutic Patents, 1999 - Taylor & Francis
Superoxide dismutase mimics (SODm) have been developed for the treatment of many diseases
which involve an excess of superoxide. … bined superoxide dismutase/catalase mimetics

Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential

I Batinić-Haberle, JS Rebouças… - Antioxidants & redox …, 2010 - liebertpub.com
Superoxide dismutase is a first line of defense against oxidative stress under physiological
… Therefore, the development of therapeutics aimed at mimicking superoxide dismutase was a …

Potential Therapeutic Applications of MnSODs and SOD‐Mimetics

R Bonetta - Chemistry–A European Journal, 2018 - Wiley Online Library
Superoxide dismutases (SODs) constitute the ubiquitous antioxidant defences … superoxide
dismutase is constantly being explored. Classes that have been developed as SOD mimetics