Superoxide dismutase improves gas exchange and pulmonary hemodynamics in premature lambs

JP Kinsella, TA Parker, JM Davis… - … journal of respiratory and …, 2005 - atsjournals.org
… the severity of respiratory distress syndrome (RDS) … lung edema, but the acute effects of
superoxide dismutase (SOD) treatment on gas exchange, lung compliance (CL), and pulmonary

Superoxide dismutase improves oxygenation and reduces oxidation in neonatal pulmonary hypertension

S Lakshminrusimha, JA Russell… - … journal of respiratory …, 2006 - atsjournals.org
… Traditionally, pulmonary hemodynamic measurements are done to assess the effect of …
Superoxide dismutase improves gas exchange and pulmonary hemodynamics in premature …

Recombinant human superoxide dismutase enhances the effect of inhaled nitric oxide in persistent pulmonary hypertension

RH STEINHORN, G ALBERT, DD SWARTZ… - … journal of respiratory …, 2001 - atsjournals.org
… the pulmonary vascular effects of superoxide dismutase (SOD… lambs with persistent
pulmonary hypertension (PPHN) … differences in pulmonary hemodynamics following treatment …

Alteration of extracellular superoxide dismutase in idiopathic pulmonary arterial hypertension

R Zhang, L Wang, QH Zhao, R Jiang, SG Gong… - Frontiers in …, 2020 - frontiersin.org
Background: Superoxide dismutases (SODs) are an important family of antioxidant enzymes
that modulate reactive oxygen species levels. It is largely unknown which SOD isoform(s) …

Superoxide dismutase restores eNOS expression and function in resistance pulmonary arteries from neonatal lambs with persistent pulmonary hypertension

KN Farrow, S Lakshminrusimha… - … of Physiology-Lung …, 2008 - journals.physiology.org
… and playing an important role in vascular tone, lung function, and metabolism of NO (9, 11, …
Superoxide dismutase improves oxygenation and reduces oxidation in neonatal pulmonary

Gene transfer of extracellular superoxide dismutase ameliorates pulmonary hypertension in rats

F Kamezaki, H Tasaki, K Yamashita… - … journal of respiratory …, 2008 - atsjournals.org
… Objectives: In the present study, we examined whether intratracheal gene transfer of
human extracellular superoxide dismutase (EC-SOD) could ameliorate monocrotaline (MCT)–…

Superoxide dismutase prevents the thrombin-induced increase in lung vascular permeability: role of superoxide in mediating the alterations in lung fluid balance.

A Johnson, MB Perlman, FA Blumenstock… - Circulation …, 1986 - Am Heart Assoc
superoxide dismutase (SOD) and SOD linked to Ficoil (mol. wt = 400,000) on the changes in
pulmonary … In the present study, the initial pulmonary hemodynamic changes after thrombin …

Extracellular superoxide dismutase overexpression can reverse the course of hypoxia-induced pulmonary hypertension

MN Ahmed, Y Zhang, C Codipilly, N Zaghloul… - Molecular …, 2012 - Springer
pulmonary hypertension (PH). We hypothesized that treatment with extracellular superoxide
dismutase … In vitrostudies using pulmonary microvascular endothelial cells showed that cells …

Superoxide dismutase with heparin prevents increased lung vascular permeability during air emboli in sheep

MR Flick, JM Hoeffel, NC Staub - Journal of Applied …, 1983 - journals.physiology.org
… concentration fell significantly more and lung lymph protein flow was less with superoxide
dismutase. There were no differences in hemodynamic variables or in lung lymph fluid flow. In …

Effects of manganese superoxide dismutase nebulization on pulmonary function in an ovine model of acute lung injury

MO Maybauer, Y Kikuchi, M Westphal, DM Maybauer… - Shock, 2005 - journals.lww.com
… eg, superoxide, in association with smoke inhalation injury. Because superoxide dismutase
converts the reactive superoxide … that nebulization of manganese superoxide dismutase (Mn-…