A supramolecular assembly strategy for hydrophilic drug delivery towards synergistic cancer treatment

H Qu, H Chen, W Cheng, Y Wang, Y Xia, L Zhang… - Acta Biomaterialia, 2023 - Elsevier
… the supramolecular assembly for hydrophilic drugs. To validate our findings, more drugs with
increasing hydrophilicity… rule may guide a wide range of hydrophilic drug delivery. Next, the …

Drug delivery by supramolecular design

MJ Webber, R Langer - Chemical Society Reviews, 2017 - pubs.rsc.org
… , with two overarching design strategies commonly used: (i) Conjugated drug acting as a
hydrophobic driving force for supramolecular assembly of fibrillar structures, or (ii) pendant …

Polymeric supramolecular systems for drug delivery

HJ Yoon, WD Jang - Journal of Materials Chemistry, 2010 - pubs.rsc.org
hydrophobic drugs. Among the various drug delivery vehicles for sustained and controlled
drug … need to develop active targeting strategies for enhancing drug delivery efficacy. Finally, …

[HTML][HTML] Supramolecular engineering of hydrogels for drug delivery

S Bernhard, MW Tibbitt - Advanced Drug Delivery Reviews, 2021 - Elsevier
Supramolecular design is an attractive strategy for … of hydrogels as it provides ease of
assembly, broad tunability, and … and release of both hydrophobic and hydrophilic drugs for use as …

Smart nanovehicles based on pH‐triggered disassembly of supramolecular peptide‐amphiphiles for efficient intracellular drug delivery

X Xu, Y Li, H Li, R Liu, M Sheng, B He, Z Gu - Small, 2014 - Wiley Online Library
… Self-assembly of stimuli-responsive SAs may be an alternative strategy for the construction
of available supramolecular … to biological stimulus to release hydrophobic drugs (Figure 4B). …

Supramolecular drug delivery system from macrocycle-based self-assembled amphiphiles for effective tumor therapy

J Chen, Y Zhang, L Zhao, Y Zhang… - … Applied Materials & …, 2021 - ACS Publications
… -assembly disintegration with an ensuing release of DOX (Scheme 1). As a consequence, a
supramolecular drug delivery strategy … vesicles are expected to possess hydrophilic interiors. …

Self assembled materials: design strategies and drug delivery perspectives

G Verma, PA Hassan - Physical Chemistry Chemical Physics, 2013 - pubs.rsc.org
assembly of small molecules in complex supramolecular structures provides a new avenue
in the development of materials for drug delivery … both hydrophilic and hydrophobic drugs, a …

Supramolecular delivery systems based on pillararenes

W Feng, M Jin, K Yang, Y Pei, Z Pei - Chemical communications, 2018 - pubs.rsc.org
… pillararenes used as hydrophilic hosts in supramolecular host–… application of SAINT
derivatives in drug delivery. In addition, … strategy for the construction of synergistic supramolecular

Peptide-based supramolecular hydrogels for local drug delivery

Z Zhang, S Ai, Z Yang, X Li - Advanced Drug Delivery Reviews, 2021 - Elsevier
… work represented an innovative strategy to enhance the solubility of highly hydrophobic
hydrophilic drugs into EISA to form nanofibers with the sustained-release of hydrophilic drugs. …

Aggregation‐induced emission featured supramolecular Tubisomes for imaging‐guided drug delivery

J Yang, X Yu, JI Song, Q Song, SCL Hall… - Angewandte …, 2022 - Wiley Online Library
assembly strategy of preparing cylindrical aggregates (tubisomes) from an amphiphilic
supramolecular … as a linker between the hydrophilic and hydrophobic segments of an amphiphilic …