Paracellular bicarbonate flux across human cystic fibrosis airway epithelia tempers changes in airway surface liquid pH
IM Thornell, T Rehman, AA Pezzulo… - The Journal of …, 2020 - Wiley Online Library
… Airway epithelia control the pH of airway surface liquid (ASL), thereby optimizing respiratory
defences. Active H + and HCO 3 − secretion by airway epithelial cells produce an ASL that …
defences. Active H + and HCO 3 − secretion by airway epithelial cells produce an ASL that …
Gastroduodenal bicarbonate secretion
DL Hogan, MA Ainsworth… - Alimentary pharmacology …, 1994 - Wiley Online Library
… epithelium is covered by an adherent mucus layer into which bicarbonate is secreted by
surface epithelial … (VIP) on duodenal surface epithelial bicarbonate secretion in the rat. Scand J …
surface epithelial … (VIP) on duodenal surface epithelial bicarbonate secretion in the rat. Scand J …
Pendrin mediates bicarbonate secretion and enhances cystic fibrosis transmembrane conductance regulator function in airway surface epithelia
… current by approximately twofold in epithelial and nonepithelial cells. We … secretion across
airway surface epithelium during inflammation and enhances electrogenic Cl − secretion …
airway surface epithelium during inflammation and enhances electrogenic Cl − secretion …
Interleukin-17A induces bicarbonate secretion in normal human bronchial epithelial cells
JL Kreindler, CA Bertrand, RJ Lee… - … of Physiology-Lung …, 2009 - journals.physiology.org
… IL-17A-induced bicarbonate secretion was cystic fibrosis transmembrane conductance …
epithelial bicarbonate secretion and implicate a mechanism by which airway surface liquid …
epithelial bicarbonate secretion and implicate a mechanism by which airway surface liquid …
Bicarbonate secretion and acid/base sensing by the intestine
HM Becker, UE Seidler - Pflügers Archiv-European Journal of Physiology, 2024 - Springer
… Major advances have been made in the assessment of surface epithelial function using
video-imaging and two-photon techniques to assess the intracellular and juxtamucosal pH in …
video-imaging and two-photon techniques to assess the intracellular and juxtamucosal pH in …
cAMP stimulates bicarbonate secretion across normal, but not cystic fibrosis airway epithelia.
JJ Smith, MJ Welsh - The Journal of clinical investigation, 1992 - Am Soc Clin Investig
… bicarbonate secretion by CF tracheal epithelia. Our results suggest that HCO- secretion …
This low ratio of airway fluid volume to secretory surface area, and the potentially high rate …
This low ratio of airway fluid volume to secretory surface area, and the potentially high rate …
Damage to the gastric epithelium activates cellular bicarbonate secretion via SLC26A9 Cl−/HCO3− exchange
ES Demitrack, M Soleimani… - American Journal of …, 2010 - journals.physiology.org
… surface epithelial cells (26, 27). Because the disulfonic stilbene DIDS is known to inhibit
acid-induced gastric surface epithelial HCO 3 − secretion (… gastric HCO 3 − secretion. It remains …
acid-induced gastric surface epithelial HCO 3 − secretion (… gastric HCO 3 − secretion. It remains …
Mechanisms of bicarbonate secretion in the pancreatic duct
MC Steward, H Ishiguro, RM Case - Annu. Rev. Physiol., 2005 - annualreviews.org
… an almost isotonic sodium bicarbonate solution. How it does … as a model for bicarbonate
transport in other epithelia. In the 10 … picture of ductal bicarbonate secretion. Those wishing to …
transport in other epithelia. In the 10 … picture of ductal bicarbonate secretion. Those wishing to …
Bicarbonate secretion: a neglected aspect of colonic ion transport
HJ Binder, V Rajendran, V Sadasivan… - Journal of clinical …, 2005 - journals.lww.com
… the surface epithelial cell. Cl absorption occurs via an apical membrane Cl-HCO 3 exchange
(ie, DRA) that may (ie, Na-dependent) or may not (ie, Na-independent) be coupled to Na-H …
(ie, DRA) that may (ie, Na-dependent) or may not (ie, Na-independent) be coupled to Na-H …
The application of bicarbonate recovers the chemical-physical properties of airway surface liquid in cystic fibrosis epithelia models
L Ferrera, V Capurro, L Delpiano, A Gianotti, O Moran - Biology, 2021 - mdpi.com
… depends on a balanced secretion of chloride and bicarbonate and the absorption … bicarbonate
secretion causes a lowering of the ASL pH which is involved in the change of the epithelia …
secretion causes a lowering of the ASL pH which is involved in the change of the epithelia …