… The latter mainly involves CFTR, the apical chloride/bicarbonate exchanger pendrin and
paracellular transport. Proton (H + ) secretion into ASL is crucial to maintain its relative acidity …

… which seems doubtful since the secretory epithelia of most, if … secretion is compromised,
the Donnan forces of secreted … that protect the apical surfaces of epithelial tissues. These …

… of anion secretion is a common feature of epithelial organs … CF airway epithelia were also
shown to absorb airway surface … urinary bicarbonate excretion at different serum bicarbonate …

… or absence of the surface epithelium. Inhibitors of Cl − and H CO 3 − secretion substantially
reduce this secretion response even when the surface epithelium is removed. Consequently, …

… A pH gradient is formed by the secretion of bicarbonate and mucus from the epithelial
cells. … epithelial surface and the bicarbonate secreted into the mucus gel thus provide pre-epithelial …

… of secretory lumens, especially since secretory epithelia are thought to … events associated
with the secretion of mucus present … of mucus to protect epithelial surfaces. The mechanisms of …

… bicarbonate transporters are the focus of the present review. This review presents examples
of the major roles of bicarbonate … by secretion of HCO 3 − on to the surface epithelium [47]. …

… and adherent to the epithelial surface, we wondered whether … The mucus secretory systems
of the surface epithelia in the … , the mucins, are formed and secreted by goblet cells. These …

… − is secreted onto the mucosal surface of most epithelia where … An important challenge in
epithelial biology has been to … ), is essential for epithelial HCO 3 − secretion, but only recently …

… − secretion is fueled by endogenous epithelial CO 2 hydration mediated by carbonic anhydrase
because acetazolamide (10 −4 M) was found to inhibit HCO 3 − secretion … gross surface …