Anion secretion by a model epithelium: more lessons from Calu‐3

J Shan, J Huang, J Liao, R Robert… - Acta …, 2011 - Wiley Online Library
surface epithelia can shift the balance of opposing absorptive and secretory processes
towards net secretion … evidence that CFTR mediates bicarbonate secretion. This preparation is …

[HTML][HTML] Putting bicarbonate on the spot: pharmacological insights for CFTR correction in the airway epithelium

M Zajac, A Lepissier, E Dréano, B Chevalier… - Frontiers in …, 2023 - frontiersin.org
… − ) and bicarbonate (HCO 3 − ) transport into the Airway SurfaceBicarbonate secretion in
the respiratory epithelium … HCO 3 − flux is measured in the WT human respiratory epithelium by …

Regulation of bicarbonate-dependent ductular bile secretion assessed by lumenal micropuncture of isolated rodent intrahepatic bile ducts.

SK Roberts, SM Kuntz, GJ Gores… - Proceedings of the …, 1993 - National Acad Sciences
epithelial cells secrete bile through transport of ions and water, the physiological mechanisms
regulating ductular bile secretion … bile secretion by interacting with cell-surface receptors …

Role of Ca2+-activated K+ channels in duodenal mucosal ion transport and bicarbonate secretion

H Dong, A Smith, M Hovaida… - American Journal of …, 2006 - journals.physiology.org
… In the proximal duodenum, the ability to neutralize gastric acid is due largely to surface
epithelial HCO 3 − secretion. In addition to protecting the duodenal mucosa from injury, DMBS …

Dynamic regulation of CFTR bicarbonate permeability by [Cl−] i and its role in pancreatic bicarbonate secretion

HW Park, JH Nam, JY Kim, W Namkung, JS Yoon… - Gastroenterology, 2010 - Elsevier
Bicarbonate performs a wide range of functions in epithelial fluids, including pancreatic juice,
airway surface … and many animals, pancreatic duct cells secrete bicarbonate (HCO 3 − ) at …

Secretion of acid and base equivalents by intact distal airways

SK Inglis, SM Wilson, RE Olver - American Journal of …, 2003 - journals.physiology.org
… Krebs-Ringer bicarbonate (KRB) containing no bafilomycin … when secreted volumes are
large than in small secreted … ducts or by surface epithelium, since secretion of acid equivalents …

Human duodenal mucosal bicarbonate secretion: evidence for basal secretion and stimulation by hydrochloric acid and a synthetic prostaglandin E1 analogue

JI Isenberg, DL Hogan, MA Koss, JA Selling - Gastroenterology, 1986 - Elsevier
… Because of the strategic location of surface epithelial mucosal bicarbonate secretion, it likely
plays a role in protecting the mucosa from acid-peptic damage. This series of experiments …

Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E–receptor subtype EP3

K Takeuchi, H Ukawa, S Kato, O Furukawa, H Araki… - Gastroenterology, 1999 - Elsevier
… HCO 3 − secretion from the surface epithelial cells is one of these mechanisms and plays
an important role in protection of the mucosa against luminal acid.4, 7, 8 This is most …

[HTML][HTML] IL-17A induces Pendrin expression and chloride-bicarbonate exchange in human bronchial epithelial cells

KM Adams, V Abraham, D Spielman, JK Kolls… - PLoS …, 2014 - journals.plos.org
… This is supported by our previous measurements of surface pH in IL-17A treated HBE
cells [20] and by microelectrode impalement studies performed under physiological ionic …

Sodium bicarbonate secretion indicated by ultrastructural cytochemical localization of HCO3 , Cl, and Na+ ions on rat bile duct brush cells

T Ogata - Medical Molecular Morphology, 2005 - Springer
… To test this possibility, rat common bile duct epithelia were … bicarbonate precipitates on
the luminal surface of MV of BCs may have been precipitated by the small amounts of secreted