Immunoregulatory functions of surfactant proteins

JR Wright - Nature Reviews Immunology, 2005 - nature.com
… -cell functions. In this article, I review the structure and functions of the surfactant proteins
SP-… It is not known whether the functions of the surfactant proteins secreted by airway cells are …

Protective role of the lung collectins surfactant protein A and surfactant protein D in airway inflammation

A Haczku - Journal of Allergy and Clinical Immunology, 2008 - Elsevier
… The acute inflammatory airway response is characterized by a time-dependent … airway
changes. These molecules, also known as the hydrophilic surfactant proteins (surfactant protein […

Function of surfactant proteins B and C

TE Weaver, JJ Conkright - Annual review of physiology, 2001 - annualreviews.org
… SP-B is the only surfactant-associated protein absolutely required for postnatal lung function
and survival. Complete deficiency of SP-B in mice and humans results in lethal, neonatal …

The role of pulmonary surfactant in obstructive airways disease

J Hohlfeld, H Fabel, H Hamm - European Respiratory Journal, 1997 - Eur Respiratory Soc
… those aspects of airway mechanics that are closely related to the function of pulmonary
surfactant. … Surfactant proteins are also synthesized, albeit to a lesser extent, in Clara cells of the …

The role of surfactant in asthma

JM Hohlfeld - Respiratory research, 2001 - Springer
surfactant functions regarding the airway compartment and highlights the impact of various
surfactant … local differences in the airways with regard to surfactant protein expression do not …

Conductive airway surfactant: surface-tension function, biochemical composition, and possible alveolar origin

W Bernhard, HP Haagsman, T Tschernig… - American journal of …, 1997 - atsjournals.org
… cells, Clara cells synthesize surfactant proteins A, B, … airway surfactant comprehensively
in terms of PL classes, PC molecular species, surfactant proteins, and surface-tension function. …

Surfactant in airway disease

G Enhorning - Chest, 2008 - Elsevier
… The surfactant phospholipids maintain the patency of the conducting airways, but this function
is inhibited by plasma proteins entering an inflamed airway. The physical behavior of the …

Host defense functions of pulmonary surfactant

JR Wright - Neonatology, 2004 - karger.com
surfactant lipids and all four surfactant proteins, SP-A, SP-B, SP-C, and SP-D [1, 2], and the
airway Clara cell which also synthesizes surfactant proteins… in surfactant protein levels during …

Surfactant protein A (SP‐A): the alveolus and beyond

KR Khubchandani, JM Snyder - The FASEB Journal, 2001 - Wiley Online Library
function of the conducting airway form of SP-A protein have been performed to date. We
hypothesize that this novel SP-A protein functions … mechanisms in the airways. There is no gene …

PLUNC: a multifunctional surfactant of the airways

J Bartlett, L Gakhar, J Penterman, P Singh… - 2011 - portlandpress.com
airway secretions contain many of the same lipid species found in alveolar surfactant, the
surfactant proteins … , suggesting that a unique protein (or group of proteins) is probably involved …