… SP-D domains in measurable protein function is largely uncharacterized. The role of the
collagenous region of surfactant protein A (SP-A), another hydrophilic surfactant-associated …

… associated with surfactant lipids are surfactant proteins A;'B, 5… , the surfactant proteins
function in the delivery of surfactant … is the most abundant protein component of surfactant, SP-A. …

… , a neck region, and a carbohydrate recognition domain. In this study, the function of the
collagenous domain was evaluated by expressing a SP-D collagen deletion mutant protein (…

… collagenous domain, a central amphipathic domain believedto play a role in phospholipid
binding, and a glycosylated carboxy-terminal domain that … Surfactant also contains at least two …

… from disruption of the perfect Gly-XY repeat pattern within the collagenous domain (10). …
This physical transformation also requires the hydrophobic surfactant protein SP-B. A second …

… Amino-terminal microsequencing gave a single collagenous sequence that corresponded
to the deduced amino-terminal amino acid sequence of the collagenous domain of rat (and …

… triple-helix formation within collagenous peptide domains, inhibited … the hydroxylation of the
collagenous domain of the polypeptide. … Integrity of the collagenous domain of SP-A but not …

… to surfactant in vitro [6]. SP-D is now recognized as a member of a family of collagenous
carbohydrate binding proteins (collagenous C-… domain (N), a triple helical collagen domain of …

… I and the collagenous pepsin fragment of Clq (Brodsky-Doyle … weight fraction of l/3 for the
collagenous domain in SP 28-36. … The collagenous tails and the globular domains are clearly …

… Because an SP-Dcdm chain has approximately one-half the mass of a wild-type
monomer, a given weight of collagenous domain dodecamer will have nearly twice as many …