A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D

R Leth-Larsen, P Garred, H Jensenius… - The Journal of …, 2005 - journals.aai.org
… Our data strongly suggest that polymorphicSurfactant protein D (SP-D) is a member of the
protein family of collectins that also includes mannose-binding lectin and surfactant protein A (…

Surfactant protein polymorphisms and neonatal lung disease

M Hallman, R Haataja - Seminars in perinatology, 2006 - Elsevier
… Indeed, the surfactant system participates in host defense on a much broader basis than …
with the common polymorphisms involving the genes encoding surfactant proteins are …

[HTML][HTML] Genetics of the hydrophilic surfactant proteins A and D

J Floros, RR Hoover - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 1998 - Elsevier
… is greatly increased when polymorphisms (eg … polymorphism, could cause and/or modify
the disease under study. It is within this context that the genes encoding the surfactant proteins (…

[HTML][HTML] Surfactant protein A and surfactant protein D variation in pulmonary disease

GL Sorensen, S Husby, U Holmskov - Immunobiology, 2007 - Elsevier
… The aim of this review is to summarize studies on genetic polymorphisms, structural variants,
and serum levels of human SP-A and SP-D and their associations with human pulmonary …

Functional polymorphisms in surfactant protein genes and chronic obstructive pulmonary disease risk: a meta-analysis

T Ma, X Liu, Z Liu - Genetic testing and molecular biomarkers, 2013 - liebertpub.com
… Our meta-analysis revealed that common polymorphisms in the … any association between
common polymorphisms in the SP-… -analysis indicates that common polymorphisms in the SP-A …

Genetic polymorphism of the binding domain of surfactant protein–A2 increases susceptibility to meningococcal disease

DL Jack, J Cole, SC Naylor, R Borrow… - Clinical infectious …, 2006 - academic.oup.com
… Variation in the genes of the surfactant proteins affects the expression and … Surfactant protein
(SP)–A and SP-D: protein structure and location of single-nucleotide polymorphisms (SNPs)…

Surfactant protein A and B genetic variants predispose to idiopathic pulmonary fibrosis

M Selman, HM Lin, M Montaño, AL Jenkins, A Estrada… - Human genetics, 2003 - Springer
Surfactant proteins play important … polymorphic variants of surfactant proteins, SP-A1,
SP-A2, SP-B, SP-C, and SP-D. One SP-A1 (6A 4 ) allele and single nucleotide polymorphisms (…

Surfactant protein Bpolymorphisms are associated with severe respiratory syncytial virus infection, but not with asthma

B Puthothu, J Forster, J Heinze, A Heinzmann… - BMC Pulmonary …, 2007 - Springer
… Interestingly, we have already described association of Surfactant protein C with RSV
bronchitis in the same cohort [20]. This might further emphasis the importance of the Surfactant

Surfactant protein D gene polymorphism associated with severe respiratory syncytial virus infection

M Lahti, J Löfgren, R Marttila, M Renko… - Pediatric …, 2002 - nature.com
… to study whether the surfactant protein D (SP-D) gene polymorphism associates with severe
… Three biallelic SP-D gene polymorphisms were genotyped. Significant differences were …

Surfactant protein B polymorphism and respiratory distress syndrome in premature twins

R Marttila, R Haataja, M Rämet, J Löfgren, M Hallman - Human genetics, 2003 - Springer
… (RDS) is partly explained by genetic variation in the surfactant proteins (SP) SP-A and SP-B. …
However, the SP-B Ile131Thr polymorphism was associated with RDS. The threonine allele …