Surfactant protein A down-regulates proinflammatory cytokine production evoked by Candida albicans in human alveolar macrophages and monocytes
S Rosseau, P Hammerl, U Maus… - The Journal of …, 1999 - journals.aai.org
… In summary, these findings strongly support an important role of SP-A in down-regulating
AM and monocyte inflammatory response to fungal challenge in the alveolar compartment. …
AM and monocyte inflammatory response to fungal challenge in the alveolar compartment. …
OSCAR is a receptor for surfactant protein D that activates TNF-α release from human CCR2+ inflammatory monocytes
AD Barrow, Y Palarasah, M Bugatti… - The Journal of …, 2015 - journals.aai.org
… Because the OSCAR:SP-D interaction promotes activation of inflammatory monocytes,
we conclude that the ultimate functional effect of SP-D depends on the balance between …
we conclude that the ultimate functional effect of SP-D depends on the balance between …
Surfactant protein A inhibits alveolar macrophage cytokine production by CD14-independent pathway
JF Alcorn, JR Wright - American Journal of Physiology-Lung …, 2004 - journals.physiology.org
… The lung collectin surfactant protein A (SP-A) has both anti-inflammatory and prophagocytic
… Lipopolysaccharide-induced tumor necrosis factor α production by human monocytes …
… Lipopolysaccharide-induced tumor necrosis factor α production by human monocytes …
Immunoregulatory functions of surfactant proteins
JR Wright - Nature Reviews Immunology, 2005 - nature.com
… surfactant proteins SP-A and SP-D in regulating host immune defence and in modulating
inflammatory … of the mannose receptor by human monocyte-derived macrophages, leading to …
inflammatory … of the mannose receptor by human monocyte-derived macrophages, leading to …
[HTML][HTML] The dual role of surfactant protein-D in vascular inflammation and development of cardiovascular disease
KB Colmorten, AB Nexoe, GL Sorensen - Frontiers in Immunology, 2019 - frontiersin.org
… SP-D is actively contributing to the inflammatory process in the artery. SP-D stimulates
LPS-induced TNF-α-secretion from CCR2+ inflammatory monocytes through binding via its …
LPS-induced TNF-α-secretion from CCR2+ inflammatory monocytes through binding via its …
Surfactant protein A regulates cytokine production in the monocytic cell line THP-1
SG Kremlev, TM Umstead… - American Journal of …, 1997 - journals.physiology.org
… In summary, the data presented in this paper demonstrate the ability of SP-A to stimulate,
and surfactant lipids to inhibit, some aspects of the inflammatory response by the THP-1 cell line…
and surfactant lipids to inhibit, some aspects of the inflammatory response by the THP-1 cell line…
Surfactant protein-A enhances uptake of respiratory syncytial virus by monocytes and U937 macrophages
FE Barr, H Pedigo, TR Johnson… - American journal of …, 2000 - atsjournals.org
… Surfactant protein (SP)-A is one of four known pulmonary surfactant–associated proteins …
production of the inflammatory cytokine TNF-α and the anti-inflammatory cytokine IL-10. …
production of the inflammatory cytokine TNF-α and the anti-inflammatory cytokine IL-10. …
Protective role of the lung collectins surfactant protein A and surfactant protein D in airway inflammation
A Haczku - Journal of Allergy and Clinical Immunology, 2008 - Elsevier
… termed a surfactant protein because of its close association with pulmonary surfactant. By …
phagocytosis through the C1q-receptor by monocytes/macrophages. The C1qR was later …
phagocytosis through the C1q-receptor by monocytes/macrophages. The C1qR was later …
[HTML][HTML] … Synthetic Reconstituted Surfactant CHF5633 on Pro- and Anti-Inflammatory Cytokine Expression in Native and LPS-Stimulated Adult CD14+ Monocytes
K Glaser, M Fehrholz, T Curstedt, S Kunzmann… - PLoS …, 2016 - journals.plos.org
… The SP-B analog is a 34-residue peptide composed of the N- and C-terminal helical regions
of surfactant protein B, but with the methionines substituted with leucines [18–20]. The SP-C …
of surfactant protein B, but with the methionines substituted with leucines [18–20]. The SP-C …
Pulmonary surfactant protein A and surfactant lipids upregulate IRAK-M, a negative regulator of TLR-mediated inflammation in human macrophages
HA Nguyen, MVS Rajaram, DA Meyer… - American Journal of …, 2012 - journals.physiology.org
… surfactant protein A (SP-A), contribute to this activation state by fine-tuning the macrophage
inflammatory … However, AMs are continuously exposed to surfactant, and the biochemical …
inflammatory … However, AMs are continuously exposed to surfactant, and the biochemical …
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