[HTML][HTML] Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional study

MW Sims, RM Tal-Singer, S Kierstein, AI Musani… - Respiratory …, 2008 - Springer
… Dexamethasone induced SP-D mRNA and protein expression in … Further, we speculate
that inhaled steroids may induce SP-D … elucidate the role of surfactant protein D in modulating …

Effect of inhaled budesonide on surfactant protein expression in asthmatic mice.

ZW Yu, JH Zhang - Allergy & Asthma Proceedings, 2008 - search.ebscohost.com
… synthesis of Clara cell secretory protein, phospholipids, and SP-A… asthmatic patients despite
corticosteroid therapy effectively … inhaled corticosteroids could regulate pulmonary surfactant

Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD

DA Lomas, EK Silverman, LD Edwards… - European respiratory …, 2009 - Eur Respiratory Soc
… or antibiotics in the month prior to the 28-day screening period or were taking oral or inhaled
steroids for >14 days consecutively in the 6 months prior to screening. All subjects were …

Steroids, surfactant and lung disease.

AD Postle, JO Warner - Thorax, 1996 - ncbi.nlm.nih.gov
steroid effect shown here was specific for surfactant proteins, or whether it represented a
more general elevation of all surfactant … , for instance, inhaled pathogens, though little direct …

Concentration-dependent cortisone adsorption and interaction with model lung surfactant monolayer

MZ Islam, SI Hossain, E Deplazes… - Molecular Simulation, 2022 - Taylor & Francis
… of a typical dose for inhaled corticosteroids and model development in the … surfactant
protein effects on the monolayer instability, we compared the clustering of the surfactant proteins

[HTML][HTML] Value of serum and induced sputum surfactant protein-D in chronic obstructive pulmonary disease

BA Ozyurek, SS Ulasli, SS Bozbas, N Bayraktar… - Multidisciplinary …, 2013 - Springer
… Sputum surfactant protein D level was found to be significantly associated with number of
years on inhaled steroid treatment (p = 0.0001). Serum surfactant protein D level was …

[HTML][HTML] Biomarkers for chronic obstructive pulmonary disease: surfactant protein D and C-reactive protein

M Dahl - American journal of respiratory and critical care …, 2008 - atsjournals.org
… The small benefits observed in lung function and health status with inhaled corticosteroids
are consistent with results from previous trials indicating that inhaled corticosteroids with or …

Developing an exogenous pulmonary surfactant-glucocorticoids association: Effect of corticoid concentration on the biophysical properties of the surfactant

A Cimato, G Facorro, MM Sarrasague - Respiratory Physiology & …, 2018 - Elsevier
Glucocorticoids (GCs) are used to treat lung disease. GCs incorporated in an exogenous
pulmonary surfactant … polarized light microscopy and surfactant activity with pulsating bubble …

The steroid mometasone alters protein containing lung surfactant monolayers in a concentration-dependent manner

MZ Islam, SI Hossain, E Deplazes, SC Saha - Journal of Molecular …, 2022 - Elsevier
… The calculation comparing a typical dose of inhaled steroids to the number of molecules used
… -dependent interaction of steroid drug mometasone with surfactant protein-containing lung …

Biophysical interaction between corticosteroids and natural surfactant preparation: implications for pulmonary drug delivery using surfactant as a carrier

YE Wang, H Zhang, Q Fan, CR Neal, YY Zuo - Soft Matter, 2012 - pubs.rsc.org
… lung disease, this study may also have implications in inhaled steroid therapy to treat asthma.
… are also suitable for systemic delivery of therapeutic agents, especially peptide and protein