… LPS activation. This study demonstrates that SP-D down-regulates LPS-elicited inflammatory
responses by altering LPS … of the correct oligomeric structure of the protein in this process. …

… of surfactant protein D with bacterial lipopolysaccharides. Surfactant protein D is an Escherichia
coli-binding protein in … of bacterial lipopolysaccharide with mouse surfactant protein C …

… The role of surfactant-associated protein (SP) A in the mediation of pulmonary responses
to bacterial lipopolysaccharide (LPS) was assessed in vivo with SP-A gene-targeted [SP-…

… We investigated the effects of surfactant lipids on SP-A-mediated LPS binding for two reasons.
First, the majority but not all of the SP-A in lavage fluid is bound to lipid (2). Second, AMs …

… deficiency in pulmonary surfactant is the main cause of … of surfactant-specific proteins that
are important, if not essential, for its function (22). Surfactant protein (SP)-A binds to surfactant …

… of a radiolabeled rough-type LPS. In addition, using LPS submitted to different chemical
treatments as well as synthetic analogs of the lipid A moiety of LPS, we established that the …

… Mice lacking SP-A produce similar levels of surfactant phospholipids and the other surfactant
proteins compared with wild-type [SP-A (+/+)] mice (21). There were also no differences in …

… Binding domains for lipid A were found in LPS-binding protein in the serum as well as on …
Recently, it was found that surfactant protein D (SP-D) is capable of interaction with LPS (12). …

… surfactant protein B [11]; (ii) the adsorption of surfactant lipids to an air-liquid interface [12,13];
and (iii) the recycling of surfactant … with LPS via the lipid A moiety of rough LPS and may be …

… Surfactant protein A protects growing cells and reduces TNF-CY activity from LPS-stimu…
In addition to its effect on surfactant lipids, surfactant protein (SP)-A promotes host defense. To …