Immunoregulatory functions of surfactant proteins

JR Wright - Nature Reviews Immunology, 2005 - nature.com
… A (SP-A) acts on amniotic-fluid macrophages to induce their migration to the pregnant
uterus and the secretion of inflammatory mediators 108 . This results in activation of uterine …

[HTML][HTML] Effects of surfactant lipids and surfactant protein A on host defense functions of rat alveolar macrophages

A Golioto, JR Wright - Pediatric research, 2002 - nature.com
… We investigated the effects of Survanta and surfactant-like liposomes in the presence and
absence of surfactant protein A (SP-A) on host defense functions of rat alveolar macrophages (…

Surfactant protein D regulates airway function and allergic inflammation through modulation of macrophage function

K Takeda, N Miyahara, YH Rha, C Taube… - American journal of …, 2003 - atsjournals.org
… lavage fluid (BALF) after administration of different doses of rat surfactant protein D (rSP-D).
Airway … Lectin-mediated interactions of surfactant protein D with alveolar macrophages. Am J …

Pulmonary surfactant protein A stimulates chemotaxis of alveolar macrophage

JR Wright, DC Youmans - American Journal of Physiology …, 1993 - journals.physiology.org
… modulates several functions of alveolar macrophages including phagocytosis, killing, and …
effect of surfactant on macrophage migration was mediated by one of the surfactant proteins, …

Surfactant protein A enhances alveolar macrophage phagocytosis of apoptotic neutrophils

TL Schagat, JA Wofford, JR Wright - The Journal of Immunology, 2001 - journals.aai.org
… Immunoregulatory proteins have been identified in the lungs. Among these proteins are
surfactant proteins A and D (SP-A and SP-D), which are in the collectin protein family of innate …

Surfactant protein A stimulates phagocytosis of specific pulmonary pathogens by alveolar macrophages

MJ Tino, JR Wright - American Journal of Physiology-Lung …, 1996 - journals.physiology.org
proteins and phospholipids (see Ref. 12 for review). While the most well-characterized function
of surfactant … points to a role for surfactant proteins, most notably surfactant protein A (SP-…

Immunomodulatory functions of surfactant

JR Wright - Seminars in respiratory and critical care medicine, 1995 - thieme-connect.com
… Which surfactant or surfactant protein preparation is most … of surfactant proteins (SPs) on
alveolar macrophage function. … -A and SP-D on macrophage function as well as some proposed …

Surfactant proteins A and D suppress alveolar macrophage phagocytosis via interaction with SIRPα

WJ Janssen, KA McPhillips, MG Dickinson… - American journal of …, 2008 - atsjournals.org
macrophage function, we sought to determine the dominant effect by adding collectins to
either J774 macrophages … As with our previous experiments, pretreating macrophages with SP-…

Surfactant protein A and surfactant protein D in health and disease

RJ Mason, K Greene… - American Journal of …, 1998 - journals.physiology.org
… However, the effect of isolated SP-A on production of oxygen radicals by alveolar macrophages
was nearly completely inhibited by surfactant phospholipids (97). McIntosh et al. (61) …

The structure and function of surfactant protein-A

F McCormack - Chest, 1997 - journal.chestnet.org
protein component of surfactant, SP-A. To more fully appreciate the role of SP-A in surfactant
function, … Vesicles of surfactant proteins and lipids in the subphase are internalized into type …