Pulmonary surfactant: functions, abnormalities and therapeutic options
… is being developed, combining recombinant peptides or proteins based on human
surfactant protein sequences with synthetic lipids such as KL-4 Surfaxin) and rSP-C …
surfactant protein sequences with synthetic lipids such as KL-4 Surfaxin) and rSP-C …
Pulmonary surfactant in health and human lung diseases: state of the art
M Griese - European Respiratory Journal, 1999 - Eur Respiratory Soc
… SP-D is the second hydrophilic surfactant protein … abnormality of bronchial surfactant in
CF and that the ongoing endobronchial inflammation results in (secondary) surfactant abnormal…
CF and that the ongoing endobronchial inflammation results in (secondary) surfactant abnormal…
Abnormal expression of surfactant protein C and lung disease
LM Nogee - American journal of respiratory cell and molecular …, 2002 - atsjournals.org
… Pulmonary surfactant is the mixture of lipids and proteins necessary to reduce alveolar …
expression of the abnormal protein during development rather than the specific protein involved. …
expression of the abnormal protein during development rather than the specific protein involved. …
[HTML][HTML] Surfactant proteins A and D: disease markers
Y Kuroki, H Takahashi, H Chiba, T Akino - Biochimica et Biophysica Acta …, 1998 - Elsevier
… idiopathic pulmonary fibrosis (IPF) and pulmonary alveolar … abnormalities including the
decreased recovery of surfactant … surfactant proteins reflects the disease activity of pulmonary …
decreased recovery of surfactant … surfactant proteins reflects the disease activity of pulmonary …
[HTML][HTML] Surfactant protein A and surfactant protein D variation in pulmonary disease
GL Sorensen, S Husby, U Holmskov - Immunobiology, 2007 - Elsevier
… that recombinant forms of the surfactant proteins are biologically active in … pulmonary
inflammatory disease. The presence of the surfactant collectins, especially SP-D, in non-pulmonary …
inflammatory disease. The presence of the surfactant collectins, especially SP-D, in non-pulmonary …
Surfactant abnormalities in idiopathic pulmonary fibrosis, hypersensitivity pneumonitis and sarcoidosis
A Gunther, R Schmidt, F Nix… - European …, 1999 - Eur Respiratory Soc
… In brief, surfactant or surfactant protein mixtures were incubated for 30 min at 378C after
brief sonication. After filling the sample chamber with 30 mL of the sample, it was immediately …
brief sonication. After filling the sample chamber with 30 mL of the sample, it was immediately …
Surfactant proteins: molecular genetics of neonatal pulmonary diseases
J Floros, P Kala - Annual review of physiology, 1998 - annualreviews.org
… Surfactant proteins have been studied in the etiopathogenesis of neonatal pulmonary …
an in-depth understanding of the pathophysiology of these and other pulmonary diseases. …
an in-depth understanding of the pathophysiology of these and other pulmonary diseases. …
The importance of surfactant on the development of neonatal pulmonary diseases
PPR Lyra, EMA Diniz - Clinics, 2007 - SciELO Brasil
… that is essential to pulmonary function. Pulmonary surfactant proteins play an important role
… It has been suggested that ABCA3 deficiency causes abnormalities in surfactant conditioning…
… It has been suggested that ABCA3 deficiency causes abnormalities in surfactant conditioning…
Diseases of pulmonary surfactant homeostasis
JA Whitsett, SE Wert, TE Weaver - Annual Review of Pathology …, 2015 - annualreviews.org
… surfactant protein and alveolar homeostasis. These studies have provided the framework
for understanding the structure and function of pulmonary surfactant… protein in abnormal …
for understanding the structure and function of pulmonary surfactant… protein in abnormal …
The role of surfactant in lung disease and host defense against pulmonary infections
SH Han, RK Mallampalli - Annals of the American Thoracic Society, 2015 - atsjournals.org
… Abnormalities in surfactant production or function are associated with several … between
genetic polymorphisms for surfactant proteins and high-altitude pulmonary edema (52), ARDS (53…
genetic polymorphisms for surfactant proteins and high-altitude pulmonary edema (52), ARDS (53…
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