Gefitinib or Erlotinib vs Chemotherapy for EGFR Mutation-Positive Lung Cancer: Individual Patient Data Meta-Analysis of Overall Survival

CK Lee, L Davies, YL Wu, T Mitsudomi… - JNCI: Journal of the …, 2017 - academic.oup.com
… This question cannot be addressed in this meta-analysis of gefitinib and erlotinib as most of
… relative PFS benefit, OS did not statistically significantly differ between gefitinib or erlotinib vs …

Erlotinib, gefitinib, or chemotherapy for EGFR mutation-positive lung cancer?

T Mitsudomi - The Lancet Oncology, 2011 - thelancet.com
… EGFR mutations predict survival benefit from gefitinib in patients with advanced lung
adenocarcinoma: a historical comparison of patients treated before and after gefitinib approval in …

[HTML][HTML] Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: a systematic review

R Feld, SS Sridhar, FA Shepherd, JA Mackay… - Journal of Thoracic …, 2006 - Elsevier
… statistically significant survival benefit for erlotinib therapy as … gefitinib as second-line or
subsequent therapy; however, a statistically significant survival benefit was not found for gefitinib

Erlotinib after gefitinib failure in relapsed non-small cell lung cancer: clinical benefit with optimal patient selection

A Hata, N Katakami, H Yoshioka, S Fujita, K Kunimasa… - Lung cancer, 2011 - Elsevier
Iressa Survival Evaluation in Lung Cancer (ISEL) study, gefitinib failed to show a survival
benefit … Conversely, erlotinib demonstrated a survival benefit for recurrent advanced NSCLC in …

[HTML][HTML] Impact on disease-free survival of adjuvant erlotinib or gefitinib in patients with resected lung adenocarcinomas that harbor EGFR mutations

YY Janjigian, BJ Park, MF Zakowski, M Ladanyi… - Journal of Thoracic …, 2011 - Elsevier
… with adjuvant cisplatin chemotherapy has no survival benefit. … of a clinical trial of perioperative
gefitinib. The surgical database … erlotinib or gefitinib delivery, disease status, and survival. …

Survival benefits from afatinib compared with gefitinib and erlotinib among patients with common EGFR mutation in first‐line setting

WC Kwok, JCM Ho, TCC Tam, MSM Ip… - Thoracic …, 2022 - Wiley Online Library
… afatinib followed by osimertinib could have survival benefit for patients with EGFR mutated
… by osimertinib in terms of survival benefit over gefitinib or erlotinib, which was not reported in …

Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations

JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
… Preplanned sub-group analyses showed significantly longer survival in the gefitinib group
… Among patients of Asian origin, treatment with gefitinib showed a survival advantage than …

… survival benefit from gefitinib in patients with advanced lung adenocarcinoma: a historical comparison of patients treated before and after gefitinib approval in Japan

T Takano, T Fukui, Y Ohe, K Tsuta… - Journal of Clinical …, 2008 - ascopubs.org
… Eight large-scale, randomized, phase III trials were conducted to evaluate the survival benefits
of gefitinib or erlotinib (Tarceva; OSI Pharmaceuticals Inc, Melville, NY), another EGFR-TKI…

[HTML][HTML] Survival benefit with erlotinib maintenance therapy in patients with advanced non-small-cell lung cancer (NSCLC) according to response to first-line …

B Coudert, T Ciuleanu, K Park, YL Wu, G Giaccone… - Annals of oncology, 2012 - Elsevier
… inhibitor (EGFR TKI) erlotinib is an established option for … Treatment with erlotinib produces
significant survival benefits … These benefits are particularly important, given that survival

Gefitinib or erlotinib as maintenance therapy in patients with advanced stage non-small cell lung cancer: a systematic review

X Chen, Y Liu, OD Røe, Y Qian, R Guo, L Zhu, Y Yin… - PloS one, 2013 - journals.plos.org
… Patients with clinical features such as female, never smoker, adenocarcinoma, Asian ethnicity
and EGFR mutation positive had more pronounced PFS benefit. Overall survival benefit