… examination were defined as having prevalent gallbladder disease at baseline. A participant’…
In the primary analysis, we used a logistic regression model with gallbladder disease as the …

… susceptibility loci for gallstone disease by use of animal models suggest genetic influences
on GBD. However, the major susceptibility loci … analysis to localize susceptibility loci for GBD. …

… The characterization of lithogenic genes in knockout and transgenic mice and the identification
of many gallstone-susceptibility loci in inbred mice provide the basis for studies of the …

… Most gallstones form and remain in the gallbladder. Many of them … For decades, it was noted
that gallbladder disease displayed … Ultrasound examination of the gallbladder detects both …

Background and Aims Genome‐wide association studies (GWAS) have identified several
risk loci for gallstone disease. As with most polygenic traits, it is likely that many genetic …

… Biobank to identify genetic susceptibility loci for gallstone disease. The genetic associations
… Lipids, obesity and gallbladder disease in women: insights from genetic studies using the …

… Genetic susceptibility in the causation of gallbladder diseases was recognized as early as
… A major gallstone susceptibility locus (Lith1) was identified in 1995 by quantitative trait locus …

… The disease susceptibility loci were mapped by identifying the genomic regions where the
… the association of gallbladder disease with approximately 2000 gene-centric loci involved in …

… in inbred mouse strains established a number of Lith loci 6,7,8,9 . … susceptibility locus on
chromosome 1p 10 , and several suggestive linkage signals overlapped with the mouse Lith loci…

… A genomewide search finds major susceptibility loci for gallbladder disease on … A
genomewide search finds major susceptibility loci for gallbladder disease on chromosome 1 in …