… the selection of switch variants. This review highlights the similarity and differences between
phenotypic switching in C. neoformans and C. gattii, the two dominant species that cause …

… In addition, the phenotypic switch variants elicit qualitatively … switch variants in animal models
of chronic cryptococcosis. … Phenotypic switching in Cryptococcus neoformans has thus far …

… Cryptococcus neoformans represents an ideal model to examine the effects of phenotypic
switching on … Phenotypic switch variants of Cryptococcus neoformans differ in gene expression …

… may also differ for switch variants and that MAb treatment can promote selection of the MC
switch variant in the setting of a switching strain. As phenotypic switching is known to change …

… Cryptococcus neoformans strains exhibit considerable phenotype … can be the result of
phenotypic switching. Phenotypic … One report suggests that hyphal switched variants may have a …

… neoformans undergoes phenotypic switching in vivo and whether this … of variants that
had already switched during in vitro propagation, we demonstrated that in vivo switching to a …

… We studied the effect of switch variants and their GXMs on protein expression of interleukin
(IL)-4, IL-10 and interferon (IFN)-γ (Table 1). IFN-γ induction was more pronounced in …

… variants (SM) and mucoid-colony variants (MC) arising from phenotypic switching of Cryptococcus
neoformans. … Cryptococcosis is an infection that occurs commonly in AIDS patients, as …

… Cryptococcus neoformans strains exhibit variability in their capsular polysaccharide, cell …
phenotypic switching results in new variants, which are characterized by altered virulence. …

… We hypothesized that phenotypic switch variants may be differently affected by IL-10
deficiency, as they elicit strikingly different inflammatory responses. Hence, the objective of this …