Sympathetic activation in the pathogenesis of hypertension and progression of organ damage

G Mancia, G Grassi, C Giannattasio, G Seravalle - Hypertension, 1999 - Am Heart Assoc
… is activated in essential HT and that this activation occurs early in the clinical course of this
disease. The mechanisms responsible for sympathetic activation … restraining sympathetic tone …

Sympathetic activation in hypertension: importance of the central nervous system

Y Hirooka - American Journal of Hypertension, 2020 - academic.oup.com
… Further, chronic NO synthase inhibition leads to neurogenic hypertension. In contrast,
inducible NOS overexpression causes hypertension with sympathetic activation due to an …

Pathogenesis of hypertension

S Oparil, MA Zaman, DA Calhoun - Annals of internal medicine, 2003 - acpjournals.org
… Finally, there is evidence of exaggerated chemoreflex function, leading to markedly enhanced
sympathetic activation in response to stimuli such as apnea and hypoxia (41). A clinical …

The sympathetic system and hypertension

M Esler - American journal of hypertension, 2000 - academic.oup.com
sympathetic activation of hypertensive patients and in the pathogenesis of human hypertension
… Though studies substantiating a role for experimental stress in causing hypertension in …

The bidirectional interaction between the sympathetic nervous system and immune mechanisms in the pathogenesis of hypertension

R Carnagarin, V Matthews, MTK Zaldivia… - British journal of …, 2019 - Wiley Online Library
… the evidence and recent advances in linking immune-mediated inflammation, sympathetic
activation and their bidirectional interactions with the development of hypertension. …

The sympathetic system in hypertension. State-of-the-art review.

FM Abboud - Hypertension, 1982 - Am Heart Assoc
… for the excessive CNS sympathetic activation or impairment of … on sympathetic drive in the
various stages of hypertension, … provoke an increase in sympathetic activity and provide a …

Sympathetic nervous system and hypertension: New evidences

G Seravalle, G Grassi - Autonomic Neuroscience, 2022 - Elsevier
… , the immune system in conjunction with sympathetic activation. The present review will …
in the development of hypertension. The paper will also examine the sympathetic mechanisms …

Mechanisms of sympathetic activation in obesity-related hypertension

M Esler, N Straznicky, N Eikelis, K Masuo… - …, 2006 - Am Heart Assoc
… of the suppression of the cardiac sympathetic outflow seen in the normotensive obese (…
-related hypertension, there is apparently no greater renal sympathetic activation than in the …

Therapeutic strategies for targeting excessive central sympathetic activation in human hypertension

JP Fisher, PJ Fadel - 2010 - Wiley Online Library
… role in triggering and sustaining the essential hypertensive … /or efferent pathways (eg
sympathetic nerve firing, adrenergic … of hypertension, excessive central sympathetic activation has …

Early and late sympathetic activation in hypertension

G Mancia, Marco Di Rienzo, Cristina … - Scandinavian …, 1998 - Taylor & Francis
… with hypertension have lately been shown to be characterized by a sympathetic activation.
i) … that in normotensive obese individuals, sympathetic nerve traffic as assessed by …