[HTML][HTML] Involvement of p38 MAPK in synaptic function and dysfunction
C Falcicchia, F Tozzi, O Arancio, DM Watterson… - International journal of …, 2020 - mdpi.com
… of p38 MAPK in the regulation of synaptic plasticity and its implication in an animal model of
neurodegeneration. In particular, recent evidence suggests the p38 MAPK α … synaptic and …
neurodegeneration. In particular, recent evidence suggests the p38 MAPK α … synaptic and …
MAPK cascade signalling and synaptic plasticity
GM Thomas, RL Huganir - Nature Reviews Neuroscience, 2004 - nature.com
… Another recently emerging story is the involvement of a 'parallel' but distinct kinase cascade
leading to the activation of p38 MAPK, which might control distinct forms of synaptic plasticity…
leading to the activation of p38 MAPK, which might control distinct forms of synaptic plasticity…
Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system
K Takeda, H Ichijo - Genes to Cells, 2002 - Wiley Online Library
… p38 MAPK inhibitors, and its availability has greatly contributed to understanding of the
biological functions of p38 MAPKs. … of the p38 pathway in the control of synaptic function has only …
biological functions of p38 MAPKs. … of the p38 pathway in the control of synaptic function has only …
The role of p38 MAPK and its substrates in neuronal plasticity and neurodegenerative disease
SAL Corrêa, KL Eales - Journal of signal transduction, 2012 - Wiley Online Library
… we will give an overview of p38 MAPK localisation, activation, and the functional role of this
… of the p38 MAPK cascade during synaptic plasticity in the hippocampus. Although p38 MAPK …
… of the p38 MAPK cascade during synaptic plasticity in the hippocampus. Although p38 MAPK …
[HTML][HTML] p38 MAPK inhibition improves synaptic plasticity and memory in angiotensin II-dependent hypertensive mice
H Dai, W Hu, L Jiang, L Li, X Gaung, Z Xiao - Scientific reports, 2016 - nature.com
… p38 MAPK inhibition rescues hippocampal LTP deficit To investigate synaptic functional
changes, we performed extracellular electrophysiological recordings on hippocampal slices at …
changes, we performed extracellular electrophysiological recordings on hippocampal slices at …
[HTML][HTML] The p38MAPK-MK2 Signaling Axis as a Critical Link Between Inflammation and Synaptic Transmission
E Beamer, SAL Corrêa - Frontiers in cell and developmental biology, 2021 - frontiersin.org
… of synaptic plasticity underlying cognitive functions. Finally, we discuss the potential of the
p38 MAPK -… , we propose that the p38 MAPK -MK2 signaling axis controls synapse strength in …
p38 MAPK -… , we propose that the p38 MAPK -MK2 signaling axis controls synapse strength in …
Targeting p38 MAPK pathway for the treatment of Alzheimer's disease
L Munoz, AJ Ammit - Neuropharmacology, 2010 - Elsevier
… protein used as a marker for synaptic function) and significantly improved behavioural
deficits. These outcomes imply that p38 MAPK inhibitors could be suitable disease modifying …
deficits. These outcomes imply that p38 MAPK inhibitors could be suitable disease modifying …
[HTML][HTML] Prions activate a p38 MAPK synaptotoxic signaling pathway
… morphology, we found that the p38 MAPK inhibitor prevented the PrP Sc -… p38 MAPK
plays an essential role in mediating the toxic effects of PrP Sc on synaptic structure and function …
plays an essential role in mediating the toxic effects of PrP Sc on synaptic structure and function …
MAPK, β-amyloid and synaptic dysfunction: the role of RAGE
N Origlia, O Arancio, L Domenici… - Expert review of …, 2009 - Taylor & Francis
… able to induce an impairment of synaptic function in the hippocampus and entorhinal cortex
… of the role of p38 MAPK in neuronal dysfunction. Phosphorylation of p38 MAPK selectively …
… of the role of p38 MAPK in neuronal dysfunction. Phosphorylation of p38 MAPK selectively …
p38 MAP kinase mediates both short-term and long-term synaptic depression in Aplysia
… The sensory-to-motor neuron synapses of Aplysia show two opposing types of synaptic …
activates p38 MAP kinase and that 5-HT inhibits the kinase. In contrast, ERK (p42) MAP kinase is …
activates p38 MAP kinase and that 5-HT inhibits the kinase. In contrast, ERK (p42) MAP kinase is …
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