Drinking water quality and chronic kidney disease of unknown etiology (CKDu): synergic effects of fluoride, cadmium and hardness of water

HMS Wasana, D Aluthpatabendi, W Kularatne… - … geochemistry and health, 2016 - Springer
… to a synergic effect of trace elements in water for etiology of … or Cd or it could be synergic
effects of F, Cd and hardness. It … which shows a strong correlation of synergic effect of F, Cd and …

Chronic kidney disease of unknown etiology and the effect of multiple-ion interactions

MWC Dharma-Wardana - Environmental geochemistry and health, 2018 - Springer
… In clarifying the synergistic action of ions, we consider (a) two types of ions, eg, Mg\(^{2+}\)
and F\(^-\), or Cd\(^{2+}\) and F\(^-\) ions, being present in water together and found to …

Cancer “causation” by infections—individual contributions and synergistic networks

H Zur Hausen, EM de Villiers - Seminars in oncology, 2014 - Elsevier
… Yet, the various ways of interacting among different factors functioning synergistically and
their … They may represent candidates for a potential etiological involvement of yet unknown

[HTML][HTML] Synergistic effects of Chinese herbal medicine: a comprehensive review of methodology and current research

X Zhou, SW Seto, D Chang, H Kiat… - Frontiers in …, 2016 - frontiersin.org
… It is important not to confuse synergistic effect with additive effect. Synergy occurs when two
effect and a synergistic effect as it is still the comparison between combination and individual …

Synergistic dopaminergic neurotoxicity of the pesticide rotenone and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease

HM Gao, JS Hong, W Zhang, B Liu - Journal of Neuroscience, 2003 - Soc Neuroscience
… Although its etiology remains unknown, PD may be the final outcome of interactions
among multiple factors, including exposure to environmental toxins and the occurrence of …

Synergistic dopaminergic neurotoxicity of MPTP and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease

HM Gao, B Liu, W Zhang, JS Hong - The FASEB Journal, 2003 - Wiley Online Library
… prevented superoxide production and the synergistic neurotoxicity. Additionally, inhibition of
… in the synergistic neurotoxicity. This study lends strong support for a multifactorial etiology of …

Synergistic combinations of antibiotics in gram-negative bacillary infections

J Klastersky, SH Zinner - Reviews of infectious diseases, 1982 - academic.oup.com
… That most frequently cited is the necessity of providing initial broad antibacterial coverage
in critically ill patients with sepsis of unknown etiology. After a serious attempt has been made …

Increased risk of hepatocellular carcinoma and liver cirrhosis in vinyl chloride workers: synergistic effect of occupational exposure with alcohol intake

G Mastrangelo, U Fedeli, E Fadda… - Environmental …, 2004 - ehp.niehs.nih.gov
… hepatitis infection, and their interactions, in the etiology of HCC and LC. Thirteen cases of …
We used Rothman’s synergy index (S) to evaluate interactions. By holding the confounding …

[HTML][HTML] The CTLA4 region as a general autoimmunity factor: an extended pedigree provides evidence for synergy with the HLA locus in the etiology of type 1 diabetes …

E Einarsdottir, I Söderström… - European Journal of …, 2003 - nature.com
… with the HLA locus on the etiology of disease (lodscore 4.20 (θ=0.0). … in this region constitutes
an etiological factor to disease … effect of individual loci in the etiology of complex diseases. …

Pemphigus: etiology, pathogenesis, and inducing or triggering factors: facts and controversies

V Ruocco, E Ruocco, AL Schiavo, G Brunetti… - Clinics in …, 2013 - Elsevier
… The synergistic effect of different subsets of autoantibodies, which target different antigens
that are anyway aimed at maintaining cell–cell cohesion, could explain the clinical and …