Synergistic interaction between amyloid and tau predicts the progression to dementia
TA Pascoal, S Mathotaarachchi, M Shin… - Alzheimer's & …, 2017 - Elsevier
… Notably, our regression models confirmed that the synergistic interaction, rather than the
sum of individual contributions of Aβ+ and p-tau+ status, determined worse baseline …
sum of individual contributions of Aβ+ and p-tau+ status, determined worse baseline …
Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology
T Kim, D Yi, MS Byun, H Ahn, JH Jung, N Kong… - Alzheimer's research & …, 2022 - Springer
… A novel point of this study is that we specifically identified that high SBP and DBP in late-life,
but not a history of hypertension, synergistically interact with in vivo cerebral amyloid …
but not a history of hypertension, synergistically interact with in vivo cerebral amyloid …
A novel, synergistic interaction between 17 β-estradiol and glutathione in the protection of neurons against β-amyloid 25–35-induced toxicity in vitro
KE Gridley, PS Green, JW Simpkins - Molecular pharmacology, 1998 - ASPET
… did not interact synergistically with E2, nor were any synergistic interactions observed …
Based on these data, we propose an estrogen-receptor independent synergistic interaction …
Based on these data, we propose an estrogen-receptor independent synergistic interaction …
Synergistic interactions are prevalent in catalytic amyloids
LR Marshall, M Jayachandran… - …, 2020 - Wiley Online Library
… Previously, we reported synergistic interactions in catalytic amyloids formed … synergistic
interactions within a family of amyloid fibrils, exploring the results of functional group interactions, …
interactions within a family of amyloid fibrils, exploring the results of functional group interactions, …
Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer's disease
TA Pascoal, S Mathotaarachchi, S Mohades… - Molecular …, 2017 - nature.com
… In conclusion, the proposed synergistic interaction between amyloid-β and tau supports
the idea of a more integrative model of AD, although it does not explicitly refute the baptist or …
the idea of a more integrative model of AD, although it does not explicitly refute the baptist or …
Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals
EC Mormino, RA Betensky, T Hedden… - JAMA …, 2014 - jamanetwork.com
… We found that Aβ and ND synergistically contributed to cognitive change, suggesting that …
Although the mechanism underlying this synergistic effect of Aβ and ND remains unclear, it is …
Although the mechanism underlying this synergistic effect of Aβ and ND remains unclear, it is …
Synergy between amyloid-β and tau in Alzheimer's disease
… Indeed, lipid-metabolism-related genes are related to the spread of both Aβ and tau
pathology in human AD 35 , and recent tau–Aβ-PET revealed a synergistic interaction between …
pathology in human AD 35 , and recent tau–Aβ-PET revealed a synergistic interaction between …
Synergistic interactions between repeats in tau protein and Aβ amyloids may be responsible for accelerated aggregation via polymorphic states
… Interactions between the Aβ amyloid and the tau protein are … the tendency to form stable
interactions between Aβ and tau … interactions, electrostatic interactions, polar interactions, and …
interactions between Aβ and tau … interactions, electrostatic interactions, polar interactions, and …
Synergistic interactions between Aβ, tau, and α-synuclein: acceleration of neuropathology and cognitive decline
LK Clinton, M Blurton-Jones, K Myczek… - Journal of …, 2010 - Soc Neuroscience
… interactions between Aβ, tau, and α-syn in vivo. Importantly, these mice also allow us to
examine the combined impact of triple brain amyloidosis … synergistic amyloidogenic interactions …
examine the combined impact of triple brain amyloidosis … synergistic amyloidogenic interactions …
Synergistic effect of amyloid-β and tau disrupts neural circuits
T Tripathi, P Kalita - ACS chemical neuroscience, 2019 - ACS Publications
… of amyloid-β (Aβ) plaques and tau-based neurofibrillary tangles. Although studies have
shown that the interaction … A recent study revealed that the interaction between Aβ and tau …
shown that the interaction … A recent study revealed that the interaction between Aβ and tau …
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