[HTML][HTML] Are blood pressure and diabetes additive or synergistic risk factors? Outcome in 8494 subjects randomly recruited from 10 populations

T Sehestedt, TW Hansen, Y Li, T Richart… - Hypertension …, 2011 - nature.com
… However, there was no synergistic interaction between diabetes and 24-h, daytime, or … (P
for interaction, 0.07⩽P⩽0.97). The only exception was a borderline synergistic effect between …

[HTML][HTML] Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology

T Kim, D Yi, MS Byun, H Ahn, JH Jung, N Kong… - Alzheimer's research & …, 2022 - Springer
… matter hyperintensities (WMHs), for the synergistic interaction effect of current BP with Aβ
on tau deposition. We first analyzed the interaction effect of global WMH volume (instead of a …

[PDF][PDF] Synergistic effects of blood pressure-lowering drugs and statins: systematic review and meta-analysis

J Sundström, G Gulliksson, M Wirén - BMJ evidence-based medicine, 2018 - ebm.bmj.com
… statistical definition of pharmacological synergism, we tested for interactions in two ways: as
… excess risk due to interaction (RERI), the attributable proportion due to interaction (AP) and …

Time course of synergistic interaction between DOCA and salt on blood pressure: roles of vasopressin and hepatic osmoreceptors

VL Brooks, KL Freeman, Y Qi - American Journal of …, 2006 - journals.physiology.org
… In DOCA-salt rats, the time course of the synergistic interaction between osmolality and … ),
we determined blood pressure (BP) and heart rate (HR) responses, using telemetric pressure

Synergistic interaction of hypertension and diabetes in promoting kidney injury and the role of endoplasmic reticulum stress

Z Wang, JM do Carmo, N Aberdein, X Zhou… - …, 2017 - Am Heart Assoc
… After 8 weeks of AC, blood pressure above the AC (and in the … acid for 6 weeks reduced
blood pressure (135±4 versus 151±… mellitus and hypertension interact synergistically to promote …

[HTML][HTML] Hyperlipidemia and hypertension have synergistic interaction on ischemic stroke: insights from a general population survey in China

C Wang, Z Du, N Ye, C Shi, S Liu, D Geng… - BMC cardiovascular …, 2022 - Springer
… significant interaction between … synergistic interaction and provide an intuitive description
for the public to increase awareness of the risk and promote healthy blood pressure and blood

[HTML][HTML] Synergistic effect of α-adducin and ACE genes causes blood pressure changes with body sodium and volume expansion

C Barlassina, NJ Schork, P Manunta, L Citterio… - Kidney international, 2000 - Elsevier
… the various proteins of the RAS could interact (or cooperate) in the … synergistic effect or
epistatic interaction between α-adducin polymorphism and ACE polymorphism on the pressure

Synergistic effects of ACE inhibition and Ang II antagonism on blood pressure, cardiac weight, and renin in spontaneously hypertensive rats

J Ménard, DJ Campbell, M Azizi, MF Gonzales - Circulation, 1997 - Am Heart Assoc
… The combination of low doses of each agent induced greater reductions in blood pressure
(… Conclusions These findings show that the synergistic interaction between the effects of low …

[HTML][HTML] Synergistic effect of smoking and blood pressure on augmentation index in men, but not in women

H Tomiyama, M Yamazaki, Y Sagawa… - Hypertension …, 2009 - nature.com
… for CVD, smoking and blood pressure were found to be … and these factors may act
synergistically to increase AI in men… without interaction, whereas only the blood pressure seems …

Synergistic effect on reduction in blood pressure with coadministration of a renin inhibitor or an angiotensin‐converting enzyme inhibitor with an angiotensin II receptor …

AA Fossa, MJ Depasquale, LJ Ringer… - Drug Development …, 1994 - Wiley Online Library
… antagonist produces a synergistic reduction in blood pressure in the … synergistic activity is
related to an interactive efkct on the metabolic elimination of oiie another. Also, if the interaction