… In conclusion, our results support the synergism between Aβ and tau pathologies as a …
Interpretation: We tested the hypothesis that the synergistic interaction between Aβ and p-tau is a …

… the increase in tau pathology observed in DLB-AD mice is mediated directly via α-syn versus
indirectly via increased Aβ pathology. However, the earliest pathological change detected …

… pathological parameters. Conclusions: We suggest that WMLs in parietal lobes and tau
pathology likely have independent but synergistic … a more low-grade AD pathology, WMLs in the …

… BP and tau deposition, there was a significant synergistic interaction effect of current SBP
and DBP with Aβ on tau deposition. The relationship between Aβ and tau deposition was …

… suggestive of both independent and interacting effects of Aβ or tau on each of these processes…
tau pathology in human AD 35 , and recent tau–Aβ-PET revealed a synergistic interaction …

… For example, co-occurrence of tau and αSyn inclusions in brain pathologies is frequent:
more than 50% of AD patients show LBs [254], while tau pathology has been observed in …

… tau pathology, brain atrophy or hypometabolism. A conceptual framework proposes that
amyloid-β and tau pathologies synergistically … synergistic interaction between amyloid-β and tau …

… tau pathologies. Thus, we aimed to determine if tau pathology depends on the synergistic
interaction … We hypothesize that APOEε4 synergistically interacts with amyloid-β to drive tau …

… causes enhanced AD pathology; there is a … the interaction between Aβ and tau pathologies
impairs the functional integrity of neural circuits in the AD brain. Thus, not only Aβ but also tau …

… In this review, we focus on the pathological properties of tau … be a critical contributor to the
pathology of Alzheimer’s disease. … work in concert to induce synergistic neurotoxicity leading to …