Rheumatoid arthritis: regulation of synovial inflammation

SE Sweeney, GS Firestein - The international journal of biochemistry & cell …, 2004 - Elsevier
Rheumatoid arthritis (RA) is a synovial inflammatory disease of unknown etiology that
occurs in about 1% of the population. The onset is typically between ages 30 and 55 years with …

Altered metabolic pathways regulate synovial inflammation in rheumatoid arthritis

U Fearon, MM Hanlon, SM Wade… - Clinical & Experimental …, 2019 - academic.oup.com
Rheumatoid arthritis is characterized by synovial proliferation… The blood vessels in the
inflamed synovium are highly … of infiltrating immune cells and inflamed resident cells, results in the …

Rheumatoid arthritis: from autoimmunity to synovitis and joint destruction

MC Boissier, L Semerano, S Challal… - Journal of …, 2012 - Elsevier
Rheumatoid arthritis (RA) is a frequent chronic inflammatory disease. It undoubtedly
belongs to autoimmune diseases with a complex network of interactions between cognate and …

Doppler ultrasound and magnetic resonance imaging of synovial inflammation of the hand in rheumatoid arthritis: a comparative study

L Terslev, S Torp‐Pedersen, A Savnik… - … of Rheumatology, 2003 - Wiley Online Library
… of synovial inflammatory activity by Doppler US and postcontrast MRI were comparable.
Estimation of synovial inflammatory … and monitoring inflammatory activity in patients with RA. …

Interaction between synovial inflammatory tissue and bone marrow in rheumatoid arthritis

E Jimenez-Boj, K Redlich, B Turk… - The Journal of …, 2005 - journals.aai.org
… In summary, we show that synovial inflammatory tissue can reach the adjacent bone …
Rheumatoid arthritis (RA) 3 is due to a chronic inflammatory process of the synovial membrane. …

Starving the synovium: angiogenesis and inflammation in rheumatoid arthritis

GS Firestein - The Journal of clinical investigation, 1999 - Am Soc Clin Investig
rheumatoid arthritis (RA) have implicated a variety of mechanisms that contribute to the initiation
and perpetuation of synovial inflammation, … -α (TNF-α) in synovial inflammation led to the …

Clinical improvement and radiological deterioration in rheumatoid arthritis: evidence that the pathogenesis of synovial inflammation and articular erosion may differ

D Mulherin, O Fitzgerald, B Bresnihan - Rheumatology, 1996 - academic.oup.com
synovial inflammation, reflected in clinical and laboratory measures of disease activity. Since
many therapies in RA suppress inflammation, … may differ from that of synovial inflammation. …

Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling

C Miao, Y Yang, X He, X Li, C Huang, Y Huang… - Cellular signalling, 2013 - Elsevier
… , such as environmental factors, smoking, inflammation, cellular proliferation … synovium
resulting in synovial inflammation, and this process occurs prior to FLS proliferation and synovial

Magnetic resonance imaging: a valuable method for the detection of synovial inflammation in rheumatoid arthritis.

P Goupille, B Roulot, S Akoka, AM Avimadje… - … of rheumatology, 2001 - jrheum.org
… We assessed MRI for the detection of synovial inflammation of hands and wrists in RA.
Therefore, the only question asked of the radiologists for each of 264 joints was whether synovitis

Reduction of synovial inflammation after anti‐CD4 monoclonal antibody treatment in early rheumatoid arthritis

PP Tak, PA Van Der Lubbe, A Cauli… - Arthritis & …, 1995 - Wiley Online Library
… To analyze the effects of anti-CD4 MAb therapy on synovial inflammation, we studied the
immunohistologic features of synovial biopsy specimens obtained before and 4 weeks after …