… as innocent synovial cells, mainly responsible for synovial homeostasis. … that rheumatoid
arthritis synovial fibroblasts (RASFs) are active drivers of joint destruction in rheumatoid arthritis. …

Recent findings have substantiated the importance of T lymphocytes to the pathogenesis of
rheumatoid arthritis (RA). Here, we review emerging data regarding genetic predisposition, …

… to persistent synovitis, however our … synovitis, and will address some potentially important
mechanisms that may facilitate the initiation and progression of rheumatoid arthritis synovitis…

Osteoclasts are multinucleated cells of hematopoietic origin and are the primary bone resorbing
cells. Numerous osteoclasts are found within the synovial tissue at sites adjacent to bone…

… cartilage destruction in rheumatoid arthritis. This scheme represents the progressive destruction
of the cartilage associated with the invading synovial pannus in rheumatoid arthritis. As …

… the synovial membrane of patients with rheumatoid arthritis (RA) (1). These include proliferation
of the synovial … changes present in the rheumatoid synovium with clinical and radiologic …

… in rheumatoid arthritis (RA) due to their prominent numbers in the inflamed synovial membrane
and at … Table 1 Activation status of synovial macrophages and/or circulating monocytes in …

Rheumatoid arthritis (RA) is a systemic, inflammatory autoimmune disorder that presents as
a symmetric polyarthritis associated with swelling and pain in multiple joints, often initially …

Dendritic cells are the major antigen-presenting and antigen-priming cells of the immune
system. We review the antigen-presenting and proinflammatory roles played by dendritic cells …

… in the case of a nonmalignant disease like rheumatoid arthritis). If anything, current notions
… synovium which, in conjunction with synovial lining cell proliferation, contributes to synovial …