… of new therapies for neglected tropical diseases. This, … their semi-synthetic derivatives and
synthetic analogues that … as their derivatives and synthetic analogues and derivatives as well. …

… -inspired semi-synthetic derivatives which have been … Other derivatives reported in this
study were also associated with pronounced potency [61]. Generally, the synthesized derivatives …

… area, is found to have activity against another disease, while drug repositioning … one disease
is derivatized or used as a template for the synthesis of derivatives active in another disease…

… for tropical diseases included … derivative (NFOH) (Figure 3), as a synthesis intermediate of
mutual prodrugs of primaquine and nitrofurazone, potentially active in Chagas’ disease. This …

… activity 101 4.7 Synthetic efforts for targeted quinoline compounds 105 4.7. 1 Synthesis of …
presented novel, naturally occurring leads and their derivatives for further exploration in the on-…

… current progress in guanidine derivatives for the … derivatives for treating both of these
diseases because of their high global incidence [13, 14]. To our knowledge, guanidine derivatives …

… fatty acid synthesis, … derivatives of vitamins are essential cofactors in metabolic processes.
Finally, nucleoside triphosphates are the immediate precursors for DNA and RNA synthesis. …

… Later, Meisenheimer's work expanded the knowledge and shed light on the synthesis of
these N-oxides derivatives making them easily obtainable [16, 17]. Furthermore, the interest in …

… out that some neglected tropical diseases were highlighted … In addition, the combination of
computational and synthetic … nitro derivatives, and NTR2, biotransforming bicyclic derivatives - …

… the fight against some neglected tropical diseases. They found that… and derivatives have also
been used in Chagas disease drug … The design, synthesis and trypanocidal activity of some …