Systematic analysis and biomarker study for Alzheimer's disease

X Li, H Wang, J Long, G Pan, T He, O Anichtchik… - Scientific reports, 2018 - nature.com
… tissues from patients with Alzheimer’s Disease (AD) will help us to understand the pathology
of this disease. In this study, we conducted the first such large systematic analysis to identify …

From a mouse: systematic analysis reveals limitations of experiments testing interventions in Alzheimer's disease mouse models

KJ Egan, HM Vesterinen, V Beglopoulos… - Evidence‐based …, 2016 - Wiley Online Library
The increasing prevalence of Alzheimer's disease ( AD ) poses a considerable socio‐economic
challenge. Decades of experimental research have not led to the development of …

Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study

G Laumet, V Chouraki, B Grenier-Boley… - … Alzheimer's disease, 2010 - content.iospress.com
We selected twenty genes from the “Top Results” list on the AlzGene database website and
assessed their association with risk of developing Alzheimer’s disease (AD) in a large, …

Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

E Nichols, CEI Szoeke, SE Vollset, N Abbasi… - The Lancet …, 2019 - thelancet.com
… of the dementia disease burden. We aimed to present the first detailed analysis of the global
… of dementia as captured by the Global Burden of Diseases, Injuries, and Risk Factors (GBD) …

[HTML][HTML] Plasma nutrient status of patients with Alzheimer's disease: systematic review and meta-analysis

SL da Silva, B Vellas, S Elemans, J Luchsinger… - Alzheimer's & …, 2014 - Elsevier
… of the current systematic review is to evaluate the presence of differences in the systemic
the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines …

Systematic analysis to identify transcriptome-wide dysregulation of Alzheimer's disease in genes and isoforms

C Fan, K Chen, J Zhou, P Wong, D He, Y Huang… - Human Genetics, 2021 - Springer
Alzheimer’s disease (AD) is one of the most common neurodegeneration diseases caused
by multiple factors. The mechanistic insight of AD remains limited. To disclose molecular …

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

L Bertram, RE Tanzi - Nature Reviews Neuroscience, 2008 - nature.com
The genetic underpinnings of Alzheimer's disease (AD) remain largely elusive despite early
successes in identifying three genes that cause early-onset familial AD (those that encode …

[HTML][HTML] Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised …

JT Yu, W Xu, CC Tan, S Andrieu, J Suckling… - Journal of Neurology …, 2020 - jnnp.bmj.com
Background Evidence on preventing Alzheimer’s disease (AD) is challenging to interpret
due to varying study designs with heterogeneous endpoints and credibility. We completed a …

Association between stroke and Alzheimer's disease: systematic review and meta-analysis

J Zhou, JT Yu, HF Wang, XF Meng… - … Alzheimer's disease, 2015 - content.iospress.com
Alzheimer's disease (AD) and stroke are common disorders of aging, but the relationship
between these two disorders remains uncertain. Recent evidence recognized that they …

[HTML][HTML] Rate of early onset Alzheimer's disease: a systematic review and meta-analysis

XC Zhu, L Tan, HF Wang, T Jiang, L Cao… - Annals of …, 2015 - ncbi.nlm.nih.gov
… The systematic review and meta-analysis was then to be … included in our systematic review
and meta-analysis. The rate … analysis of all studies in random effect model. The pooled …