… of concurrent radiosensitizing systemic therapy and definitive radiotherapy (chemoradiotherapy)
have improved survival among patients with head and neck cancer and especially …

… Head and neck malignancies remain challenging to treat, requiring a multidisciplinary
approach, with surgery, radiotherapy, and systemic therapy serving as key components of the …

… outcomes in head and neck cancer (HNC). This systematic review aims to provide insight into
the … on oncologic and functional outcomes in oral cavity, pharyngeal, and laryngeal cancer. …

… neck cancer (HNC) encompasses a heterogeneous group of upper aerodigestive tract
malignancies that together comprise the seventh most common cancer … This section reviews risk …

Most head and neck cancers are squamous cell carcinomas that develop in the upper
aerodigestive epithelium after exposure to carcinogens such as tobacco and alcohol. Human …

… These trials indicate that chemotherapy can have meaningful systemic activity in head and
neck cancer. Unless local or regional control can be improved, however, there is unlikely to …

… This review will highlight these important advances in the treatment of patients with head
and neck cancer (Table 1) and emphasize the ways in which molecular biology is likely to affect …

… A systematic review in 2005 described HPV DNA prevalences of 23.5% and 24.0% for
oral and laryngeal SCC, respectively 78 . A subsequent meta-analysis in 2014 revealed that …

… While our systematic review leads us to question whether HPV has a specific role in tonsil
SCC, the number of studies is small. The inconsistency between studies using ELISA and …

… This review is limited to head and neck cancers of squamous cell histology, which constitute
more than 90% of head and neck cancers. Because treatment of head and neck cancers is …