… Understanding the molecular mechanisms of chronic inflammation in AT remains a major …
between NLRP3 inflammasome and obesity, IR and T2DM, we performed a systematic review …

… How NLRP3 responds to those … the NLRP3 inflammasome is not fully understood. In this
review, we summarize our current understanding of the mechanisms of NLRP3 inflammasome …

… Additionally, the anthracycline doxorubicin induces systemic inflammation associated with
IL… Obviously, our understanding of the NLRP3 inflammasome molecular mechanisms needs to …

… , which drives subsequent systemic immune responses … NLRP3, which is essential for
NLRP3 inflammasome activation 66 . Although some studies suggest that NLRP3 inflammasome …

… of NLRP3 on systemic inflammation of PD. A recent study reported that kaempferol (Ka), a
small molecule inhibitor of NLRP3 inflammasome … a better understanding of CAPS. The lethal, …

… in our understanding of the activation and intrinsic regulation of the NLRP3 inflammasome
… approaches that target the NLRP3 inflammasome and show potential for clinical translation. …

… review, we discuss the current understanding of the mechanistic details of NLRP3 …
understanding of the molecular details involved in the priming/licensing step of NLRP3 …

… Several single amino acid substitutions in NLRP3 are causative for systemic inflammation
… Major progress has also been made in our understanding of how intracellular LPS triggers …

… evidence has greatly improved our understanding of the mechanisms by which the NLRP3
… cells, proposing that NLRP3 activation is involved in both systemic and local inflammation in …

… In this review, we address the current understanding of the control of NLRP3 activity
which can be divided into two coordinated processes referred to as priming and activation. In …