Systemic response to ambient particulate matter: relevance to chronic obstructive pulmonary disease
SF van Eeden, A Yeung, K Quinlam… - Proceedings of the …, 2005 - atsjournals.org
… An integral component of the systemic inflammatory … of leukocytes and platelets into the
circulation. The level of this … leukocytes into the circulation as part of the systemic response; …
circulation. The level of this … leukocytes into the circulation as part of the systemic response; …
Particulate matter induces translocation of IL-6 from the lung to the systemic circulation
T Kido, E Tamagawa, N Bai, K Suda… - American journal of …, 2011 - atsjournals.org
… To determine the A–V gradient of IL-6 across the lung, which allowed us to estimate the
translocation of IL-6 from the lungs into the systemic circulation, we collected arterial and venous …
translocation of IL-6 from the lungs into the systemic circulation, we collected arterial and venous …
Direct and indirect effects of particulate matter on the cardiovascular system
… Human exposure to particulate matter (PM) elicits a variety of responses on the … system
directly by entry into the systemic circulation. This process causes myocardial dysfunction through …
directly by entry into the systemic circulation. This process causes myocardial dysfunction through …
Inhalation of ultrafine and fine particulate matter disrupts systemic vascular function
KW Rundell, JR Hoffman, R Caviston… - Inhalation …, 2007 - Taylor & Francis
… This study identified acute effects on the systemic circulatory system after PM 1 inhalation
during exercise that could be an important component in explaining the reported increase in …
during exercise that could be an important component in explaining the reported increase in …
Systemic inflammatory response induced by particulate matter air pollution: the importance of bone-marrow stimulation
SF Eeden, JC Hogg - … of Toxicology and Environmental Health, Part …, 2002 - Taylor & Francis
… particulate matter air pollution induces a systemic inflammatory response that includes the
release of inflammatory mediators into the circulation … this systemic response to particulate air …
release of inflammatory mediators into the circulation … this systemic response to particulate air …
Systemic translocation of particulate matter–associated metals following a single intratracheal instillation in rats
JG Wallenborn, JK McGee… - Toxicological …, 2007 - academic.oup.com
… metals from the lungs into systemic circulation may be partly … translocate to systemic circulation
and extrapulmonary … the lung may be released into systemic circulation at different rates …
and extrapulmonary … the lung may be released into systemic circulation at different rates …
Systemic and vascular effects of circulating diesel exhaust particulate matter
N Bai, SF van Eeden - Inhalation toxicology, 2013 - Taylor & Francis
… We found the bulk of particles in the spleen suggesting that the majority of particles reached
the systemic circulation and were not trapped in the liver following the venous injection. …
the systemic circulation and were not trapped in the liver following the venous injection. …
Particulate matter, air pollution, and blood pressure
RD Brook, S Rajagopalan - Journal of the American Society of …, 2009 - Elsevier
… A short-term increase in fine particulate matter air pollution (… In addition, fine particles can
instigate a systemic pro-… be capable of reaching the systemic circulation upon inhalation and …
instigate a systemic pro-… be capable of reaching the systemic circulation upon inhalation and …
[HTML][HTML] Endothelial dysfunction in the pulmonary artery induced by concentrated fine particulate matter exposure is associated with local but not systemic …
… liberation of inflammatory cytokines from the pulmonary tissue to the systemic circulation,
leading to increases in markers of systemic inflammation such as C reactive protein (Peters et al…
leading to increases in markers of systemic inflammation such as C reactive protein (Peters et al…
Systemic microvascular dysfunction and inflammation after pulmonary particulate matter exposure
TR Nurkiewicz, DW Porter, M Barger… - Environmental …, 2006 - ehp.niehs.nih.gov
… The second hypothesis proposes that PM deposited in the lung gains access to the systemic
circulation and directly interacts with target tissues. After exposure, PM deposition has been …
circulation and directly interacts with target tissues. After exposure, PM deposition has been …
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