… The NLRP3 inflammasome has been linked … NLRP3 inflammasome complex and its activation
in disease, and detail the current therapies that modulate either the NLRP3 inflammasome …

… enhances chronic low-grade inflammation and NLRP3 inflammasome activation during
HFD feeding 102 . However, oleic acid, which is an unsaturated fatty acid, negatively regulates …

… mechanisms of inflammasome activation are still … NLRP3 inflammasome activation via
dopamine D1 receptor (DRD1). DRD1 signaling negatively regulates NLRP3 inflammasome via a …

… and then inhibit the NLRP3 inflammasome activation [59]. Systemic inflammation has been
… In a mouse model focusing on systemic inflammatory response syndrome, the researchers …

… systemic inflammation in CVD and highlights the NLRP3 inflammasome as a therapeutic
target… rs10754555 associates with higher NLRP3 mRNA expression and NLRP3 inflammasome …

… fibrogenesis in NLRP3 –/– mice 14 days after induction of pancreatitis (Supplementary
Figure 10). In summary, the deletion of the NLRP3 inflammasome reduced the systemic immune …

… link systemic inflammation to aging remain unclear. Here we detail a mechanism by which
the Nlrp3 inflammasome controls systemic low-grade age-related “sterile” inflammation in …

… the Nlrp3 inflammasome participates in immune dysfunction leading to chronic inflammation
… We show that Nlrp3 inflammasome activation in obesity promotes macrophage-mediated T …

… inflammatory diseases. This review extensively discusses NLRP3 inflammasome-related …
the design of therapeutic strategies for NLRP3 inflammasome-related diseases. Additionally, …

… chronic inflammation, NLRP3 inflammasomes and insulin resistance. Regarding the role of
the NLRP3 inflammasome … and endogenous stimulators of the inflammasome during T2D. It …