DNA methylation in systemic lupus erythematosus

CM Hedrich, K Mäbert, T Rauen, GC Tsokos - Epigenomics, 2017 - Taylor & Francis
DNA methylation patterns in SLE, underlying molecular defects and their effect on immune
cell function. We discuss the potential of DNA methylation … -α reduces DNA methylation of the …

DNA methylation and systemic lupus erythematosus

E Balada, J ORDI‐ROS… - … New York Academy of …, 2007 - Wiley Online Library
… anti-DNA and antihistone antibodies. All this supports the hypothesis … methylation inhibition
is sufficient to cause a lupus-like illness. We have also checked the global DNA methylation

Impaired DNA methylation and its mechanisms in CD4+ T cells of systemic lupus erythematosus

Y Zhang, M Zhao, AH Sawalha, B Richardson… - Journal of autoimmunity, 2013 - Elsevier
… to DNA hypomethylation in lupus. In this review, we summarize current understanding of T
cell DNA methylation changes and the consequently altered gene expressions in lupus, and …

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

BM Javierre, AF Fernandez, J Richter… - Genome …, 2010 - genome.cshlp.org
… sequence analyses of DNA methylation to investigate … signs often overlap: systemic lupus
erythematosus (SLE), … widespread changes in the DNA methylation status of a significant …

Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus

M Jeffries, M Dozmorov, Y Tang, JT Merrill, JD Wren… - Epigenetics, 2011 - Taylor & Francis
… to the pathogenesis of lupus. To understand the extent and nature of … DNA methylation in
lupus T cells, we performed a genome-wide DNA methylation study in CD4 + T cells in lupus

DNA methylation: its contribution to systemic lupus erythematosus

I Sekigawa, M Kawasaki, H Ogasawara… - Clinical and …, 2006 - Springer
… suggested that abnormalities of DNA methylation may contribute to the development of
systemic lupus erythematosus (SLE). Here we review the possible role of DNA methylation in the …

The key culprit in the pathogenesis of systemic lupus erythematosus: aberrant DNA methylation

H Wu, M Zhao, L Tan, Q Lu - Autoimmunity reviews, 2016 - Elsevier
… summarize the association between aberrant DNA methylation of immune cells and SLE, …
caused by DNA methylation, and to better understand the roles of aberrant DNA methylation in …

DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

J Imgenberg-Kreuz, JC Almlöf, D Leonard… - Annals of the …, 2018 - ard.bmj.com
… To search for cis-acting genetic variants that regulate DNA methylation in SLE, we analysed
DNA methylation levels against the genotypes of single nucleotide polymorphisms (SNPs) …

DNA methylation in systemic lupus erythematosus

I Sekigawa, M Okada, H Ogasawara, H Kaneko… - Lupus, 2003 - journals.sagepub.com
… (SLE), although the relationship between DNA methylation and SLE has long been the …
DNA methylation in the induction of SLE, we reviewed the relationship between DNA methylation

Global DNA methylation, DNMT1, and MBD2 in patients with systemic lupus erythematosus

CC Liu, TT Ou, CC Wu, RN Li, YC Lin, CH Lin… - Lupus, 2011 - journals.sagepub.com
… The global methylation level of DNA was significantly … were no significant differences in the
methylation level and the … a significantly lower level of DNA methylation than the controls. The …