The pharmacological treatment, mainly based on diuretics, of isolated systolic hypertension (ISH)
has recently been shown to reduce the risk of stroke and coronary heart disease in the …

… controlled hypertension is explained by poor SBP control. In the SELECT study we have
studied a group of elderly hypertensive patients with stage 2 systolic hypertension diagnosed by …

… Systolic Hypertension in the Elderly Program (SHEP) is a randomized, blinded test of the
efficacy of antihypertensive … women who had isolated systolic hypertension and were at least 60 …

… in patients with only isolated systolic hypertension, and trials conducted only in Black
patients, in whom the superior BP-lowering efficacy of diuretics and CCAs is well established.[8] …

… Systolic hypertension, the predominant form of hypertension in patients aged over 50–60
years, is a growing health issue as the Asian population ages. Elevated systolic blood … systolic …

… antihypertensive therapy. Despite the availability of effective antihypertensives, poor control
of systolic hypertension … , assessing the efficacy of aliskiren compared with ramipril in systolic …

… This study set out to compare the antihypertensive efficacy and safety of two different … the
event of insufficient antihypertensive control. The primary efficacy parameter was the proportion …

… Compared with CCBs or thiazide-like diuretics (chlorthalidone or indapamide), ACEi/ARBs
have distinctly less efficacy in patients with isolated systolic hypertension. However, ACEi/…

… with at least 2 antihypertensive agents is usually needed to achieve appropriate blood
pressure (BP) control in patients with isolated or predominant systolic hypertension. A currently …

… [4] The efficacy of diuretics and ↑-blockers in the prevention of cardiovascular … to assess
the efficacy of various antihypertensive drugs, commonly used in France, to reduce systolic (SBP…