Impact of the treatment of isolated systolic hypertension on behavioral variables: results from the Systolic Hypertension in the Elderly Program

WB Applegate, S Pressel, J Wittes, J Luhr… - Archives of Internal …, 1994 - jamanetwork.com
… of isolated systolic hypertension in the Systolic Hypertension in the Elderly Program cohort
had … that medical treatment of isolated systolic hypertension does not cause deterioration in …

Effect of treating isolated systolic hypertension on the risk of developing various types and subtypes of stroke: the Systolic Hypertension in the Elderly Program (SHEP)

HM Perry Jr, BR Davis, TR Price, WB Applegate… - Jama, 2000 - jamanetwork.com
… of all strokes in elderly patients with isolated systolic hypertension. There were also …
Elderly patients and their physicians should be diligent in treating isolated systolic hypertension

Morbidity and mortality in the Systolic Hypertension in the Elderly Program (SHEP) pilot study.

HM Perry Jr, WM Smith, RH McDonald, D Black… - Stroke, 1989 - Am Heart Assoc
… of the Systolic Hypertension in the Elderly Program was a randomized, double-blind,
placebo-controlled trial of drug therapy for isolated systolic hypertension. It followed 551 elderly

Pulse pressure and risk of cardiovascular events in the systolic hypertension in the elderly program

V Vaccarino, AK Berger, J Abramson, HR Black… - The American journal of …, 2001 - Elsevier
systolic hypertension is common among the elderly and is accompanied by elevated pulse
pressure. Treatment of isolated systolic hypertension … a greater extent than systolic pressure. …

The systolic hypertension in the elderly program (SHEP): an intervention trial on isolated systolic hypertension

JL Probstfield, WB Applegate, NO Borhani… - … Hypertension. Part A …, 1989 - Taylor & Francis
The Systolic Hypertension in the Elderly Program (SHEP) is a randomized double-blind … if
antihypertensive treatment of isolated systolic hypertension (ISH) [systolic blood pressure (SBP…

Atrial fibrillation and isolated systolic hypertension: the systolic hypertension in the elderly program and systolic hypertension in the elderly program-extension study

TD Vagaonescu, AC Wilson, JB Kostis - Hypertension, 2008 - Am Heart Assoc
… the Systolic Hypertension in the Elderly Program database to assess the incidence of atrial
fibrillation in the elderly hypertensive … The Systolic Hypertension in the Elderly Program was a …

Systolic Hypertension in the Elderly Program (SHEP): antihypertensive efficacy of chlorthalidone

SB Hulley, CD Furberg, B Gurland, R McDonald… - The American journal of …, 1985 - Elsevier
… We conclude that chlorthalidone treatment of elderly patients with isolated systolic
hypertension is acceptable to most and produces a substantial lowering of BP. These conclusions …

Predictors of cardiovascular events and mortality in the Systolic Hypertension in the Elderly Program pilot project

D SIEGEL, L KULLER, NB LAZARUS… - American journal of …, 1987 - academic.oup.com
Systolic Hypertension in the Elderly Program pilot project, all of our patients had isolated
systolic hypertension at baseline with systolic … of elevation of systolic pressure at baseline did …

Systolic Hypertension in the Elderly Program (SHEP). Part 1: rationale and design.

NO Borhani, WB Applegate, JA Cutler, BR Davis… - …, 1991 - Am Heart Assoc
… 1-4, 7, 14, 16-20 Moreover, these studies demonstrate that elevated SBP with normal
DBP (ie, isolated systolic hypertension [ISH]) is associated with increased long-term risks of …

Systolic hypertension in the elderly: addressing an unmet need

DA Duprez - The American journal of medicine, 2008 - Elsevier
… The Systolic Hypertension in the Elderly Program (SHEP) study showed that active blood
pressure treatment significantly reduced rates of nonfatal stroke by 36%, total coronary heart …